Antenatal Neuroprotective Magnesium Sulfate in Very Preterm Infants and Its Association With Feeding Intolerance.

Author: CanpolatFuat Emre, ElbayiyevSarkhan, Kanmaz KutmanHayriye Gozde, OguzSerife Suna, OguzYuksel, Ozer BekmezBuse, TaymanCuneyt, UygurDilek

Paper Details 
Original Abstract of the Article :
Magnesium sulfate (MgSO 4 ) treatment is widely used for fetal neuroprotection despite the controversy concerning the side effects. There is limited data regarding the impact of various cumulative maternal doses and neonatal serum magnesium (Mg) levels on short-term neonatal morbidity and mortality....See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/37580867

データ提供:米国国立医学図書館(NLM)

Antenatal Magnesium Sulfate: Neuroprotection and Feeding Intolerance in Preterm Infants

The field of [neonatal medicine] is constantly seeking ways to improve the health and development of [preterm infants]. This study investigates the complex relationship between [antenatal magnesium sulfate (MgSO4) treatment] and [neonatal outcomes] in [very preterm infants]. The researchers analyzed data on the impact of [cumulative maternal doses of MgSO4] and [neonatal serum magnesium levels] on short-term [neonatal morbidity and mortality]. Their findings suggest that [higher neonatal serum Mg levels] are associated with [increased feeding intolerance] in very preterm infants. However, the study did not find a significant association between [MgSO4 treatment] and [short-term neonatal morbidity or mortality].

Navigating the Complexities of Antenatal MgSO4

This study sheds light on the potential complexities of [antenatal MgSO4 treatment] in [very preterm infants]. While the findings do not support a direct link between [MgSO4 treatment] and [short-term morbidity or mortality], they highlight the potential association between [higher neonatal serum Mg levels] and [feeding intolerance]. This information is valuable for clinicians managing the care of very preterm infants, emphasizing the need for careful monitoring of serum Mg levels and addressing potential feeding difficulties.

Health Implications and Lifestyle Applications

This study underscores the importance of carefully considering the potential risks and benefits of [antenatal MgSO4 treatment] in [very preterm infants]. While MgSO4 is widely used for [fetal neuroprotection], the findings suggest that it may be associated with [feeding intolerance] in some infants. Further research is needed to understand the underlying mechanisms involved and develop strategies to minimize potential complications related to MgSO4 treatment.

Dr.Camel's Conclusion

The care of very preterm infants is like navigating a vast and often unpredictable desert landscape. This study sheds light on the complexities of antenatal MgSO4 treatment, reminding us that even well-established practices can have unexpected consequences. As we continue our journey through the sands of scientific discovery, we eagerly await further research that may lead to even more effective and safer strategies for improving the health and development of very preterm infants.

Date :
  1. Date Completed 2023-10-31
  2. Date Revised 2023-10-31
Further Info :

Pubmed ID

37580867

DOI: Digital Object Identifier

00005176-990000000-00460

Related Literature

SNS
PICO Info
in preparation
Languages

English

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