Wilson Disease: A Case Report of Psychosis Preceding Parkinsonism.

Author: AzadiAzadeh, ClarkeAntonia J, DunkertonSophie, HalmagyiGabor M, ThompsonElizabeth O, TischStephen, WorthingtonJohn M, XiePeter

Paper Details 
Original Abstract of the Article :
BACKGROUND A first psychotic episode requires the exclusion of toxic-metabolic, inflammatory, infective, and neoplastic causes. Wilson disease is a rare, autosomal recessive disorder of copper metabolism and can present with neuropsychiatric symptoms secondary to copper accumulation in the brain. CA...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441581/

データ提供:米国国立医学図書館(NLM)

When the Mind and Body Collide: Wilson Disease and its Neuropsychiatric Manifestations

This case report delves into the complex world of Wilson disease, a rare genetic disorder that disrupts copper metabolism. Imagine a camel struggling to navigate a shifting desert landscape, affected by an imbalance in its internal environment. This case study presents a patient with Wilson disease who experienced psychosis before the onset of parkinsonism. This highlights the often-overlooked neuropsychiatric manifestations of this condition. The authors emphasize the importance of considering Wilson disease in the differential diagnosis of psychosis, particularly when other signs and symptoms are present. The study demonstrates the crucial role of early diagnosis and treatment in managing this potentially treatable condition.

The Hidden Sands of Wilson Disease

This case report emphasizes the need for comprehensive evaluation when diagnosing psychosis. Just like a camel needs to carefully assess its surroundings to navigate the desert, clinicians should consider a wide range of potential causes, including rare disorders like Wilson disease. This study underscores the importance of early detection and treatment for optimal patient outcomes.

The Need for Awareness

This study highlights the importance of raising awareness about Wilson disease and its diverse presentations. Just like a camel needs to be aware of its surroundings to avoid danger, healthcare professionals need to be aware of rare conditions to provide effective care. This research encourages ongoing research and education to improve early diagnosis and management of Wilson disease.

Dr. Camel's Conclusion

This case report serves as a reminder that neuropsychiatric symptoms can be a manifestation of underlying medical conditions, like Wilson disease. It highlights the importance of comprehensive evaluation and early intervention to manage these conditions effectively.
Date :
  1. Date Completed 2023-08-17
  2. Date Revised 2023-08-23
Further Info :

Pubmed ID

37583127

DOI: Digital Object Identifier

PMC10441581

Related Literature

SNS
PICO Info
in preparation
Languages

English

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