Effect of Calcitriol in Inhibiting the Cancer Cell Growth and Promoting Apoptosis in ErbB2-positive Breast Cancer Cells.

Author: MariappanEsakkimuthukumar, NatarajanJawahar, SelvarajJubie, SelvarajNagaraj Balan, SwaroopAkey Krishna, ThangaveluPrabha

Paper Details 
Original Abstract of the Article :
Targeted therapies, specifically ErbB family tyrosine kinase inhibitors, have demonstrated potential for improving outcomes in patients with ErbB2-positive breast cancer. Despite their effectiveness, these therapies are associated with limitations, including high costs, side effects, drug resistance...See full text at original site
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引用元:
https://doi.org/10.2174/1871520623666230822100006

データ提供:米国国立医学図書館(NLM)

Repurposing Drugs: A New Oasis in Breast Cancer Treatment

The quest for effective breast cancer treatments continues, much like an explorer seeking a hidden oasis in the vast desert. This research explores the potential of repurposing existing drugs, such as calcitriol, to combat this prevalent disease. While targeted therapies, like ErbB family tyrosine kinase inhibitors, have shown promise, they are often associated with high costs, side effects, and resistance. This study delves into the possibility of using calcitriol, a naturally occurring hormone, to inhibit cancer cell growth and promote apoptosis (programmed cell death) in ErbB2-positive breast cancer cells. This approach offers a potential solution to the limitations of current therapies.

The Promise of Repurposed Drugs: A New Oasis

The study's findings suggest that calcitriol may be a promising agent for treating ErbB2-positive breast cancer. While more research is needed, this study is a beacon of hope, suggesting that calcitriol may hold the key to more effective and less toxic treatments. This research is like discovering a new oasis in the desert of breast cancer research, offering a refreshing alternative to current approaches.

Navigating the Desert of Breast Cancer Treatment

Breast cancer is a challenging journey, much like navigating a vast desert with unexpected obstacles. This research reminds us that we must continue to seek new solutions, explore novel avenues, and utilize existing tools in innovative ways. This research is a testament to the perseverance and creativity of scientists who are constantly seeking to improve the lives of those affected by this disease.

Dr. Camel's Conclusion

The repurposing of existing drugs like calcitriol offers a promising new path in the fight against breast cancer. This study suggests that we may be able to unlock the potential of existing drugs to create more effective and less toxic treatments. The quest for a cure for breast cancer continues, but with innovative approaches like this, we are closer to finding solutions that will improve the lives of countless individuals.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-10-24
Further Info :

Pubmed ID

37608657

DOI: Digital Object Identifier

10.2174/1871520623666230822100006

Related Literature

SNS
PICO Info
in preparation
Languages

English

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