[Fundamental and clinical studies on cefixime in pediatrics].

Author: ArakiK, KitamuraI, KurashigeT, MoriokaN, MoritaH, OguraH

Paper Details 
Original Abstract of the Article :
We have evaluated cefixime (CFIX) fine granules for pharmacokinetics and therapeutic effectiveness in children with infections. The results were summarized as follows. Pharmacokinetic parameters after the oral administration of single doses of 1.5 mg and 6.0 mg per kg body weight in a cross-over des...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3761544

データ提供:米国国立医学図書館(NLM)

Cefixime in Pediatrics: A Promising Antibiotic for Children

This study investigates the pharmacokinetics and therapeutic effectiveness of cefixime, an antibiotic, in children with infections. The study involved a pharmacokinetic study of cefixime in a child after oral administration of single doses of 1.5 mg and 6.0 mg per kg body weight, followed by a clinical trial involving 19 children with various infections. The pharmacokinetic study revealed that cefixime reached peak serum concentrations within 2 to 4 hours and had a biological half-life of approximately 2.5 hours. The clinical trial demonstrated a high effectiveness rate of cefixime in treating bacterial infections in children, with no significant side effects reported. The only abnormal laboratory finding was a slight elevation of GOT and GTP in one child. This study suggests that cefixime is a safe and effective antibiotic for treating bacterial infections in children.

Cefixime: A Safe and Effective Antibiotic Option for Children

This study provides strong evidence for the efficacy and safety of cefixime in treating bacterial infections in children. The findings suggest that cefixime could be a valuable therapeutic option for pediatric patients, particularly those with infections that are commonly resistant to other antibiotics.

Addressing the Challenges of Pediatric Infectious Diseases

This study highlights the importance of research and development in pediatric infectious diseases. By identifying safe and effective antibiotics for children, researchers can contribute to better patient outcomes and address the challenges associated with treating bacterial infections in this vulnerable population.

Dr.Camel's Conclusion

This study is a beacon of hope in the vast desert of pediatric infectious diseases. Cefixime, with its proven efficacy and safety profile, offers a valuable tool for treating bacterial infections in children. It's a reminder that even in the face of challenging medical conditions, we can find solutions that improve the lives of our youngest patients.

Date :
  1. Date Completed 1986-10-30
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

3761544

DOI: Digital Object Identifier

3761544

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SNS
PICO Info
in preparation
Languages

Japanese

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