[Fundamental and clinical studies on cefixime in pediatric field].

Author: KidaK, MatsudaH, MiyazakiM, MuraseM

Paper Details 
Original Abstract of the Article :
Cefixime (CFIX) was evaluated for pharmacokinetics, therapeutic effectiveness on infection, safety, and bacteriological effectiveness in pediatrics. The following is a summary of the results. Pharmacokinetics in 4 children, 2 each receiving a single dose of 1.5 mg or 6.0 mg per kg body weight, were ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3761545

データ提供:米国国立医学図書館(NLM)

Cefixime: A Promising Antimicrobial for Pediatric Use

The world of pediatric medicine is a delicate balance, requiring a special understanding of the needs of young patients. This study explores the pharmacokinetics, therapeutic effectiveness, safety, and bacteriological effectiveness of cefixime in children. It's like carefully navigating a delicate sandcastle, ensuring that every aspect of the treatment is well-considered and safe for young patients.

Pharmacokinetic Studies in Children

The study involved pharmacokinetic evaluations in four children who received single doses of cefixime. The researchers meticulously measured serum concentrations and half-lives, providing valuable insights into how cefixime is absorbed, distributed, and eliminated in young bodies.

Therapeutic Effectiveness and Bacteriological Evaluation

The study also evaluated the therapeutic effectiveness of cefixime in 19 children with infections. The researchers observed excellent or good outcomes in all cases. They also conducted a bacteriological evaluation in 10 children, demonstrating the ability of cefixime to successfully eradicate pathogens.

Dr. Camel's Conclusion

This study offers valuable insights into the potential of cefixime as a safe and effective antimicrobial for pediatric use. The research highlights its impressive therapeutic effectiveness and provides valuable pharmacokinetic data. However, more research is needed to fully understand the long-term effects of cefixime in children.

Date :
  1. Date Completed 1986-10-30
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

3761545

DOI: Digital Object Identifier

3761545

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SNS
PICO Info
in preparation
Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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