Paper Details 
Original Abstract of the Article :
Phosphorus is an essential element for all living organisms and is involved in various biological pathways. A severe hypophosphatemia can lead to serious complications (acute heart or respiratory failure, rhabdomyolysis, hemolysis…) and increases mortality in patients at risk. Various drugs are know...See full text at original site
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引用元:
https://doi.org/10.1016/j.therap.2023.07.007

データ提供:米国国立医学図書館(NLM)

Drug-Related Hypophosphatemia: A Silent Threat in the Desert of Health

Phosphorus is a vital mineral for all living beings, playing a crucial role in various biological processes. But when phosphorus levels dip too low (hypophosphatemia), it can lead to serious complications. This study aims to shed light on the drugs commonly associated with hypophosphatemia and the underlying mechanisms. Utilizing data from the French Pharmacovigilance Network, researchers identified tenofovir disoproxil, ferric carboxymaltose, denosumab, zoledronic acid, and hydrochlorothiazide as the most frequently reported culprits. The study underscores the importance of healthcare professionals being vigilant in monitoring patients taking these medications to detect and address hypophosphatemia early. It's like being aware of the dangers lurking in a desert, such as hidden sandstorms or treacherous ravines. Awareness can help prevent potential harm.

Unveiling the Hidden Dangers in Medication

The study reveals a significant disproportionality in the occurrence of hypophosphatemia linked to the five drugs mentioned above. This observation highlights the importance of meticulous monitoring of patients receiving these medications. Hypophosphatemia related to tenofovir disoproxil, for instance, can occur years after its initiation and potentially lead to renal tubulopathy. This is like finding a deceptive oasis in the desert, initially appearing harmless but eventually revealing a dangerous hidden depth.

Navigating Medication and Hypophosphatemia

The study emphasizes the crucial role of healthcare professionals in detecting and managing drug-induced hypophosphatemia. Early identification and intervention are vital to prevent serious complications. Patients should be aware of the potential risks associated with certain medications and consult with their healthcare providers about any concerns. This collaborative approach is like navigating a desert together; staying alert and informed can help avoid potential dangers and ensure a safe journey.

Dr. Camel's Conclusion

The study sheds light on the hidden dangers of drug-induced hypophosphatemia. By understanding the potential risks associated with certain medications and maintaining open communication with healthcare providers, we can navigate this complex landscape and protect ourselves from the dangers lurking within. Remember, even in a vast desert, vigilance and awareness are key to staying safe and healthy.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-08-27
Further Info :

Pubmed ID

37634954

DOI: Digital Object Identifier

10.1016/j.therap.2023.07.007

Related Literature

SNS
PICO Info
in preparation
Languages

English

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