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Metformin combined with spironolactone vs. metformin alone in polycystic ovary syndrome: a meta-analysis.

Author: HuangLeneng, HuangSikai, RenWenrui, WuJinghua, YeYuyin, ZengHuamin, ZhangYing, ZhouLingru

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Combining metformin with spironolactone may be an effective and safe treatment for polycystic ovary syndrome (PCOS), but further research is needed to confirm its efficacy and safety.
Paper Details　
Original Abstract of the Article :
Due to its high heterogenicity and unclear etiology, there is currently no specific treatment for polycystic ovary syndrome (PCOS). Metformin, as an insulin sensitizer, combined with spironolactone, an antiandrogen medication, may exert complementary effects on PCOS. We therefore performed a meta-an...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449574/

データ提供：米国国立医学図書館（NLM）

Metformin and Spironolactone: A Potential Duo for PCOS Treatment

Polycystic ovary syndrome (PCOS), a complex endocrine disorder, affects millions of women worldwide, causing a range of symptoms from irregular periods to infertility. This meta-analysis explores the efficacy and safety of combining metformin, an insulin sensitizer, with spironolactone, an antiandrogen medication, for PCOS treatment.

A Potential Oasis in the Desert of PCOS

PCOS, with its diverse symptoms, can feel like navigating a vast and unforgiving desert. This meta-analysis examines the potential of combining metformin and spironolactone as a new oasis, offering relief and improved outcomes for women with PCOS.

A Complementary Approach to PCOS Management

The meta-analysis suggests that combining metformin and spironolactone may have complementary effects in treating PCOS, potentially leading to improved outcomes in areas like menstrual regularity and hormonal balance. It's like having a double-pronged approach to navigating the desert, tackling the challenges from multiple angles.

Dr. Camel's Conclusion

This meta-analysis highlights the potential benefits of combining metformin and spironolactone for PCOS treatment. The study suggests that this complementary approach may offer improved outcomes for women with PCOS, providing a potential oasis in the desert of their condition. Remember, navigating the complexities of PCOS requires a multi-faceted approach, and this combination therapy holds promise for improving the lives of women affected by this disorder.

Date :
  1. Date Completed 2023-08-29
  2. Date Revised 2023-08-31
Further Info :

Pubmed ID

37635987

DOI: Digital Object Identifier

PMC10449574

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Languages

English

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