Paper Details 
Original Abstract of the Article :
The first description of the in vivo visualization of somatostatin receptor-positive tumors in patients was based on the use of a radioiodine (<sup>123</sup>I) labelled somatostatin analogue (Krenning et al. 1989). In the years that followed an Indium-111 (<sup>111</sup>In) labelled somatostatin ana...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元:
https://pubmed.ncbi.nlm.nih.gov/37658556

データ提供:米国国立医学図書館(NLM)

Radiopharmaceuticals for NETs: A Journey from Diagnosis to Therapy

The field of [neuroendocrine tumor (NET) treatment] is constantly evolving, with [radiopharmaceuticals] playing an increasingly pivotal role. This research provides a comprehensive overview of the use of [radiopharmaceuticals] in both the [diagnosis] and [therapy] of [NETs], tracing their development from early [scintigraphic imaging] techniques to the latest advancements in [targeted radionuclide therapy (PRRT)].

From Imaging to Therapy: The Evolution of Radiopharmaceuticals in NET Management

The journey began with the development of [radiolabeled somatostatin analogues], paving the way for [in vivo visualization] of [somatostatin receptor-positive tumors]. Over time, these radiopharmaceuticals have evolved, with the introduction of [positron emission tomography (PET)] imaging, allowing for improved [sensitivity] and [tumor detection]. The next logical step was to harness the power of [radiopharmaceuticals] for [therapeutic purposes], leading to the development of [PRRT], which utilizes [high administered activity] of [radiolabeled somatostatin analogues] to induce [tumor shrinkage] in patients with [inoperable or metastasized NETs].

Dr.Camel's Conclusion

This review highlights the remarkable progress made in the field of [NET management] using [radiopharmaceuticals]. These advancements offer hope for patients with [NETs], providing tools for both [accurate diagnosis] and [effective therapy]. The future holds even greater promise, with ongoing research exploring the potential of [targeted alpha-particle therapy (TAT)] and other innovative approaches to improve [treatment outcomes] for individuals with [NETs].

Date :
  1. Date Completed 2023-11-02
  2. Date Revised 2023-11-02
Further Info :

Pubmed ID

37658556

DOI: Digital Object Identifier

37658556

Related Literature

SNS
PICO Info
in preparation
Languages

English

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