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Rapid access to antiretroviral therapy, receipt of naltrexone, and strengths-based case management versus standard of care for HIV viral load suppression in people with HIV who inject drugs in Russia (LINC-II): an open-label, randomised controlled trial.

Author: BlokhinaElena, BusharaNatalia, ChengDebbie M, GnatienkoNatalia, KrupitskyEvgeny, LioznovDmitry, LunzeKarsten, QuinnEmily, RajAnita, RosenSydney, SametJeffrey H, TruongVe

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

This randomized controlled trial evaluated a multicomponent intervention for linking people with HIV in addiction treatment to HIV care. The intervention significantly increased the odds of HIV viral load suppression at 12 months (47% vs 23% in the standard-of-care group), highlighting its potential to advance UNAIDS goals.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Antiretroviral therapy (ART) coverage in Russia is low for people with HIV who inject drugs. HIV and addiction treatment in Russia are not well integrated. We aimed to evaluate an intervention to link people with HIV in addiction treatment to HIV care to achieve HIV viral load suppressio...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/37659841

データ提供：米国国立医学図書館（NLM）

Integrating HIV and Addiction Care: A Multicomponent Intervention for Viral Suppression

This study explores the effectiveness of a multicomponent intervention to link people with HIV who inject drugs (PWID) to HIV care and achieve viral load suppression. The study evaluated the impact of an intervention that included rapid access to antiretroviral therapy (ART), naltrexone for opioid use disorder, and strengths-based case management, compared to standard of care.

A Multicomponent Intervention: Improved Viral Suppression in PWID

The study found that participants in the multicomponent intervention group had significantly higher odds of achieving undetectable HIV viral load at 12 months compared to those in the standard of care group. This finding suggests that this integrated approach, combining HIV and addiction treatment, can effectively improve viral suppression among PWID.

Improving HIV Care for PWID: The Importance of Integrated Services

This research highlights the need for integrated HIV and addiction care services to improve viral suppression among PWID. The study emphasizes the importance of a multicomponent intervention approach that addresses both the medical and psychosocial needs of this vulnerable population. This research underscores the importance of breaking down silos in healthcare systems to deliver comprehensive and effective care for individuals with complex health challenges.

Dr. Camel's Conclusion

Imagine a desert where travelers are seeking a path to a safe and healthy destination. This study is like a guide, demonstrating the effectiveness of a multicomponent intervention to help PWID navigate this path and achieve viral suppression. The study emphasizes the importance of integrated services to address the unique challenges faced by this population. This research reminds us that providing comprehensive care, like creating a safe passage through a desert, can lead to improved outcomes and a brighter future for those in need.
Date :
  1. Date Completed 2023-09-04
  2. Date Revised 2023-11-19
Further Info :

Pubmed ID

37659841

DOI: Digital Object Identifier

NIHMS1930170

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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