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Methods, Detection Rates, and Survival Outcomes of Screening for Head and Neck Cancers: A Systematic Review.

Author: EskanderAntoine, FuRui, HaqueAminul, RivalElla, SykesEdward A, WeisbrodNatalie

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A systematic review of 16 studies involving 4.7 million adults found that screening programs for oral and nasopharyngeal cancers may improve diagnosis and survival. Universal screening improved overall survival but not cancer-specific survival, while targeted screening was associated with improved overall and cancer-specific survival. Further research is needed to optimize risk stratification, address screening adherence, and assess societal cost-effectiveness.
Paper Details　
Original Abstract of the Article :
IMPORTANCE: Head and neck cancers (HNCs) are often diagnosed at advanced clinical stages during their symptomatic phase, leading to a reduced treatment window and poor survival. Screening programs have been suggested as a mitigation strategy. OBJECTIVE: To examine the effectiveness of current HNC s...See full text at original site
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引用元：
https://doi.org/10.1001/jamaoto.2023.3010

データ提供：米国国立医学図書館（NLM）

Methods, Detection Rates, and Survival Outcomes of Screening for Head and Neck Cancers: A Systematic Review

Early detection is crucial for improving survival outcomes in [head and neck cancers (HNCs)]. This systematic review examines the effectiveness of [screening programs] for HNCs, focusing on their impact on diagnosis and survival. The authors conducted a comprehensive analysis of 16 studies, evaluating various screening methods and their impact on detection rates and survival outcomes. Their findings highlight the potential benefits of screening programs for HNCs, particularly for specific cancer subsites and risk groups.

Potential Benefits of Screening for Head and Neck Cancers

The review suggests that screening programs can significantly increase the detection rate of localized HNCs, leading to earlier diagnosis and potentially improved survival outcomes. This is particularly true for risk-targeted screening programs, which focus on individuals with higher risk factors for specific cancer subsites. The desert of HNC diagnosis is often characterized by late detection, leading to more aggressive disease and poorer outcomes. Screening programs offer a potential way to find oases of early detection and improve treatment outcomes.

Implications for Public Health and Cancer Prevention

This systematic review underscores the importance of implementing effective screening programs for HNCs, particularly for individuals with higher risk factors. The findings emphasize the need for continued research into optimizing screening methods, improving adherence rates, and addressing the cost-effectiveness of screening programs. The desert of cancer prevention is vast, but with a focused approach to screening, we can find new oases of hope for patients and their families.

Dr. Camel's Conclusion

This systematic review highlights the potential benefits of screening programs for head and neck cancers, particularly for specific cancer subsites and risk groups. The findings underscore the need for continued research into optimizing screening methods, improving adherence rates, and addressing the cost-effectiveness of these programs.

Date :
  1. Date Completed 2023-11-10
  2. Date Revised 2023-11-10
Further Info :

Pubmed ID

37796524

DOI: Digital Object Identifier

10.1001/jamaoto.2023.3010

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Article Analysis
・Effective treatment of head and neck cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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