Effects of long-term ergoloid mesylates ('Hydergine') administration in healthy pensioners: 5-year results.

Author: HuberF, KöberleS, PresteleH, SpiegelR

Paper Details 
Original Abstract of the Article :
Five-year results are reported of a controlled long-term comparative study to assess the effects of ergoloid mesylates (1.5 mg 3-times daily) and placebo on medical, psychological and electrophysiological variables. Initially, 148 healthy elderly volunteers of both sexes were included. Eighty-nine s...See full text at original site
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引用元:
https://doi.org/10.1185/03007998609110447

データ提供:米国国立医学図書館(NLM)

The Effects of Ergoloid Mesylates on Healthy Pensioners

The study, "Effects of long-term ergoloid mesylates ('Hydergine') administration in healthy pensioners: 5-year results," delves into the potential effects of ergoloid mesylates on healthy elderly individuals. Like a traveler navigating a vast and unpredictable desert, the researchers sought to understand how this drug might affect the physical and mental well-being of older adults over a five-year period. The study involved a double-blind design, where participants were randomly assigned to receive either ergoloid mesylates or a placebo.

Maintaining Physical and Mental Health

While the study didn't find any significant differences between the two groups in terms of medical or psychological outcomes, it did reveal several interesting trends. For example, those taking ergoloid mesylates reported fewer subjective complaints like dizziness, cardiac symptoms, and leg cramps. Additionally, there was a lower incidence of pathological ECG findings and fewer participants needed to take digitalis. These findings, like hidden oases in the desert, suggest that ergoloid mesylates might play a role in maintaining physical and mental health in healthy older individuals.

A Potential Prophylactic Effect

One interesting observation was that there were more disease-related and symptom-related dropouts in the placebo group compared to those taking ergoloid mesylates. This suggests that ergoloid mesylates might have a prophylactic effect, like a protective shield against the harsh conditions of aging. The study also noted that some individuals who left the double-blind trial for medical reasons showed improvement after starting ergoloid mesylates, further supporting the idea that this drug could have a protective effect against age-related health decline.

Dr. Camel's Conclusion

This study is like a journey through a desert landscape, where the subtle effects of ergoloid mesylates become apparent over time. The researchers, like seasoned travelers, uncovered clues suggesting that this drug might have a beneficial effect on maintaining physical and mental health in older individuals. While more research is needed, the study offers valuable insights into the potential role of ergoloid mesylates in helping older adults navigate the challenges of aging.

Date :
  1. Date Completed 1987-01-14
  2. Date Revised 2019-09-08
Further Info :

Pubmed ID

3780290

DOI: Digital Object Identifier

10.1185/03007998609110447

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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