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Comparative Efficacy and Side Effect Profiles of Interventions for Pediatric Saliva Control: A Cohort Study.
Author: AbsoudMichael, BreaksAnne, FairhurstCharlie, MahonyAoife, PapandreouApostolos
Original Abstract of the Article :
OBJECTIVE: To compare efficacy and side effect profile data on conservative, behavioral, pharmacological, and surgical treatments used for pediatric saliva control. STUDY DESIGN: A cohort study of children (n = 483) referred to a specialty Saliva Control service between May 2014 and November 2019 w...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元:
https://doi.org/10.1016/j.jpeds.2023.113803
データ提供:米国国立医学図書館(NLM)
Treatment Options for Pediatric Saliva Control
Drooling, or excessive saliva production, can be a real challenge for kids, especially when it impacts their social lives and self-esteem. This study, carried out by a team of experts, offers a comprehensive look at different treatment options for pediatric drooling. The study investigated the efficacy and side effects of a variety of interventions, including behavioral therapy, medication, and surgery, in a large cohort of children referred for saliva control. The researchers used standardized tools to assess the severity of drooling and the effectiveness of each treatment.
Botulinum Toxin and Duct Transpositional Surgery: Effective Solutions for Severe Drooling
The study revealed that intraglandular botulinum toxin A (BTX-A) injections and saliva duct transpositional surgery were the most effective treatments for severe drooling. BTX-A injections, which temporarily block nerve signals to the salivary glands, resulted in the greatest improvement in drooling. Duct transpositional surgery, which reroutes the salivary ducts to a different location, also demonstrated significant improvement in saliva control.
Oral Anticholinergics: A Good First-Line Option for Mild Drooling
For milder cases of drooling, oral anticholinergics, such as glycopyrronium bromide and trihexyphenidyl, were found to be effective and well-tolerated. These medications reduce saliva production by blocking the action of acetylcholine, a neurotransmitter that stimulates salivary glands. Inhaled ipratropium bromide, another anticholinergic medication, was found to be less effective than oral anticholinergics.
Dr.Camel's Conclusion
This research offers a valuable resource for parents and healthcare professionals struggling with pediatric drooling. The study helps us understand the nuances of different treatment options and their effectiveness. Like an oasis in the desert of drooling, this research provides a roadmap to help families find the best treatment for their child's specific situation.
Date :
- Date Completed n.d.
- Date Revised 2023-11-19
Further Info :
Related Literature
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