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Twice-daily versus once-daily vaginal dinoprostone gel for induction of labor at term: A randomized controlled trial.

Author: DavidMarion, HciniNajeh, JankyEustase, MandelbrotLaurent, Moustapha DrameM, Paule GueyeHenriette, PenagerCécile, SibiudeJeanne

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Twice-daily administration of intravaginal PGE2 for induction of labor at term was associated with a significantly shorter induction-to-delivery time compared to once-daily administration, without increasing maternal or neonatal morbidity. Patients in the twice-daily group reported higher satisfaction with their induction.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: The aim of this study was to compare twice-daily versus once-daily administration of intravaginal PGE2 for induction of labor at term. Efficacy, safety, and patient satisfaction were evaluated. STUDY DESIGN: For this single-center, randomized, comparative, open-label, two-arm, and parall...See full text at original site
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引用元：
https://doi.org/10.1016/j.ejogrb.2023.11.016

データ提供：米国国立医学図書館（NLM）

Optimizing Induction of Labor with Vaginal Dinoprostone Gel

This study delves into the realm of obstetrics, exploring the optimal frequency of administration for vaginal dinoprostone gel, a prostaglandin E2 analog used to induce labor at term. The researchers conducted a randomized controlled trial comparing twice-daily versus once-daily administration of vaginal dinoprostone gel in pregnant women with medical indications for labor induction.

Twice-Daily Dinoprostone Gel: A More Effective Approach

The study revealed that twice-daily administration of vaginal dinoprostone gel resulted in a significantly shorter induction-to-delivery interval compared to once-daily administration. Importantly, this shorter induction time was not associated with an increase in maternal or neonatal complications.

Implications for Labor Induction and Patient Satisfaction

This research suggests that twice-daily administration of vaginal dinoprostone gel may be a more efficient and effective strategy for inducing labor at term, potentially improving patient satisfaction.

Dr.Camel's Conclusion

Just as a desert traveler needs to carefully plan their journey, expectant mothers and their healthcare providers must carefully consider the optimal approach to labor induction. This study sheds light on the potential benefits of twice-daily administration of vaginal dinoprostone gel, offering a valuable tool for optimizing this crucial aspect of childbirth.
Date :
  1. Date Completed n.d.
  2. Date Revised 2023-11-22
Further Info :

Pubmed ID

37992422

DOI: Digital Object Identifier

10.1016/j.ejogrb.2023.11.016

Related Literature

Article Analysis
・Effects of dinoprostone
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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