[Fundamental and clinical studies on aztreonam in the field of obstetrics and gynecology].

Author: KamiishiH, MatsuzakiY, MinaguchiH, UemuraT, YanagihashiT

Paper Details 
Original Abstract of the Article :
The following results were obtained through the fundamental and clinical studies of aztreonam (AZT), a new monobactam antibiotic, in obstetrics and gynecology. Satisfactory tissue penetration was not recognized in 3-5 hours after intravenous injection of 1 g. However, the concentration was more than...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3834143

データ提供:米国国立医学図書館(NLM)

Aztreonam: A Novel Monobactam Antibiotic for Obstetric and Gynecological Infections

The field of [obstetric and gynecological infections] often requires the use of [antibiotics] to combat bacterial pathogens. This study investigated the efficacy and safety of [aztreonam (AZT)], a [novel monobactam antibiotic], in treating infections in this clinical setting. The researchers conducted [both fundamental and clinical studies] to evaluate the [pharmacokinetic profile, tissue penetration, and clinical effectiveness] of AZT. Their findings highlight the potential of this antibiotic for treating infections in pregnant women and those with gynecological conditions.

Aztreonam Demonstrates Effective Tissue Penetration and Clinical Efficacy

The study found that [AZT achieved therapeutic concentrations in various tissues] after intravenous administration, including the uterus. The researchers also observed [clinical efficacy] of AZT in treating [puerperal endometritis, vaginal wall abscess, postoperative lymphocele infection, and infected ovarian cyst]. Importantly, the study found that [AZT was well-tolerated] with [no significant side effects or adverse reactions]. These results suggest that AZT may be a valuable treatment option for infections in obstetrics and gynecology.

Expanding the Antibiotic Arsenal: Addressing the Challenges of Obstetric and Gynecological Infections

This study underscores the importance of [expanding the antibiotic armamentarium] to effectively combat [obstetric and gynecological infections]. The authors demonstrate the potential of [aztreonam] as a safe and effective treatment option in this clinical setting. Continued research is needed to further evaluate the use of AZT in different types of infections and patient populations.

Dr. Camel's Conclusion

Imagine a desert oasis where a healing spring, like aztreonam, offers a potent remedy for infections plaguing pregnant women and those with gynecological conditions. This study reveals the promising therapeutic potential of this antibiotic, providing a valuable addition to the medical toolkit for addressing these challenging infections.

Date :
  1. Date Completed 1986-05-23
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

3834143

DOI: Digital Object Identifier

3834143

Related Literature

SNS
PICO Info
in preparation
Languages

Japanese

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