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Comparison of propafenone and disopyramide for treatment of chronic ventricular arrhythmias: placebo-controlled, double-blind, randomized crossover study.

Author: AmbrosioniE, BertacciniP, BracchettiD, CantelliI, NaccarellaF, PalmieriM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Propafenone is more effective than disopyramide in treating frequent and complex premature ventricular contractions (PVCs) and non-sustained ventricular tachycardia. It also has fewer side effects.
Paper Details　
Original Abstract of the Article :
In a double blind, placebo-controlled study, the efficacy of propafenone, a new antiarrhythmic drug was compared to that of disopyramide. Sixteen patients with frequent and complex premature ventricular contractions (PVCs) were studied by serial 24-hour ambulatory monitoring, while they were receivi...See full text at original site
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引用元：
https://doi.org/10.1016/0002-8703(85)90647-7

データ提供：米国国立医学図書館（NLM）

Heart Rhythms: Finding the Right Treatment

Heart arrhythmias, like a desert mirage, can be a deceptive and unsettling experience. This study compares the effectiveness of two medications, propafenone and disopyramide, for treating chronic ventricular arrhythmias. The research found that propafenone was more effective in reducing the frequency of arrhythmias and had fewer side effects. These findings offer valuable guidance for selecting the most appropriate treatment for patients experiencing this challenging heart condition.

Navigating the Desert of Heart Health

The study highlights the importance of individualized treatment approaches for heart arrhythmias. Imagine having a trusty camel guide who can navigate the treacherous terrain of the desert, choosing the safest and most efficient path. This study provides similar guidance for healthcare professionals, helping them select the best treatment options for their patients.

Finding a Pathway to Recovery

This research emphasizes the importance of finding the right medication to manage heart arrhythmias. It's like discovering a hidden oasis in the desert, offering a place of respite and healing. By working with healthcare providers and exploring different treatment options, individuals can find a path to a healthier and more stable heart rhythm.

Dr. Camel's Conclusion

This study underscores the importance of finding the right treatment for heart arrhythmias, much like navigating a desert with a compass that helps us find our way to a healthier heart rhythm.
Date :
  1. Date Completed 1985-05-01
  2. Date Revised 2019-06-26
Further Info :

Pubmed ID

3885700

DOI: Digital Object Identifier

10.1016/0002-8703(85)90647-7

Related Literature

Article Analysis
・Side Effects of disopyramide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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