Comparison of Vivalan (viloxazine hydrochloride) with imipramine in the treatment of depression. A double-blind study.

Author: BattistinL, MaistrelloI, SantonastasoP

Paper Details 
Original Abstract of the Article :
Twenty-eight hospitalized patients with depressive illness entered a double-blind trial to compare viloxazine hydrochloride (Vivalan) with imipramine. Both drugs produced a statistically significant improvement in the depressive symptoms as early as the 7th day, measured by the HRS. A side effects c...See full text at original site
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引用元:
https://doi.org/10.1111/j.1600-0447.1979.tb03580.x

データ提供:米国国立医学図書館(NLM)

Comparing Vivalan (Viloxazine Hydrochloride) with Imipramine for Depression

The field of [psychiatry] is constantly seeking [effective treatments] for [depression], a prevalent and debilitating condition. This study compares the [efficacy and safety] of [vivalan (viloxazine hydrochloride)] and [imipramine] in [treating hospitalized patients with depressive illness]. The researchers conducted a [double-blind trial] involving [28 patients] to assess the [clinical improvement and side effects] of each medication.

Vivalan and Imipramine: Similar Efficacy, Different Side Effects

The study found that [both vivalan and imipramine] produced [statistically significant improvements] in [depressive symptoms] as early as [day 7]. However, the two medications differed in their [side effect profiles]. [Vivalan] was associated with [fewer anticholinergic effects] but [more frequent upper gastrointestinal side effects] compared to [imipramine].

A Potential Alternative Treatment for Depression: Vivalan

This research highlights the [potential of vivalan] as a [treatment option] for [depression]. While [both vivalan and imipramine] were found to be [effective], [vivalan] offered a [different side effect profile], potentially making it a [suitable alternative] for patients who [experience adverse effects] with [traditional antidepressants]. This study encourages [further research] to [compare vivalan with other antidepressants] and [establish its long-term efficacy and safety].

Dr.Camel's Conclusion

This study is a valuable expedition into the desert of [depression treatment], providing insights into the [efficacy and side effect profiles] of [vivalan and imipramine]. The findings suggest that [vivalan] may offer a [viable alternative] for patients seeking [relief from depression] with [minimal anticholinergic effects].

Date :
  1. Date Completed 1980-01-19
  2. Date Revised 2019-08-15
Further Info :

Pubmed ID

388987

DOI: Digital Object Identifier

10.1111/j.1600-0447.1979.tb03580.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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