Comparison of in vitro activity of undecylenic acid and tolnaftate against athlete's foot fungi.

Author: AmselL P, CravitzL, VanderWykR, ZahryS

Paper Details 
Original Abstract of the Article :
Undecylenic acid and tolnaftate were tested in an in vitro test system to evaluate their relative "killing time" efficacy against Trichophyton mentagrophytes, Trichophyton rubrum, and Epidermophyton floccosum. Commercial products containing these active agents were tested similarly. The pure active ...See full text at original site
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引用元:
https://doi.org/10.1002/jps.2600680338

データ提供:米国国立医学図書館(NLM)

Undecylenic Acid vs. Tolnaftate: A Battle of Antifungal Agents

This study compares the antifungal activity of undecylenic acid and tolnaftate, both commonly used to treat athlete's foot. Imagine two desert oases, each with its own unique water source and potential to sustain life.

Antifungal Efficacy: A Head-to-Head Comparison

The research finds that undecylenic acid and tolnaftate demonstrate similar antifungal activity in vitro, but the commercial product containing undecylenic acid appears to be more effective against the test organisms. It's like comparing two desert oases, each offering nourishment and sustenance but with differing levels of effectiveness. The study highlights the importance of considering the specific formulation and delivery method of antifungal agents when evaluating their clinical effectiveness.

Choosing the Right Antifungal: A Practical Approach

The study provides valuable information for clinicians to consider when choosing an antifungal treatment for athlete's foot. It's like selecting the best oasis for a caravan, considering factors such as water quality, availability, and overall suitability. By understanding the relative efficacy of different antifungal agents, clinicians can make informed decisions to optimize patient outcomes and ensure the most effective treatment.

Dr. Camel's Conclusion

This study compares the antifungal activity of undecylenic acid and tolnaftate, two common treatments for athlete's foot. It's like exploring two desert oases, each offering potential solutions for a common problem. The research reveals that while both agents demonstrate similar in vitro activity, the commercial product containing undecylenic acid appears to be more effective against the test organisms. This study provides valuable insights for clinicians when selecting antifungal treatments, ensuring the best possible outcomes for patients battling athlete's foot.

Date :
  1. Date Completed 1979-05-23
  2. Date Revised 2019-07-10
Further Info :

Pubmed ID

423138

DOI: Digital Object Identifier

10.1002/jps.2600680338

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Languages

English

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