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Local and Gastrointestinal reactions to intravenously administered cefoxitin and cefuroxime.

Author: AlestigK, NorrbyR, TrollforsB

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Cefoxitin and cefuroxime caused thrombophlebitis in 3 and 1 cases, respectively, and diarrhea in 4 and 5 cases, respectively, during intravenous treatment for at least 14 days. Most patients with diarrhea had decreased renal function or received higher doses of the antibodies.
Paper Details　
Original Abstract of the Article :
Side effects of cefoxitin and cefuroxime were noted in 2 different studies during intravenous treatment for at least 14 days. In the cefoxitin group of 33 patients thrombophlebitis was observed in 3 cases and diarrhoea in 4 cases. In the cefuroxime group of 31 patients 1 case of thrombophlebitis was...See full text at original site
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引用元：
https://doi.org/10.3109/inf.1979.11.issue-4.12

データ提供：米国国立医学図書館（NLM）

Side Effects of Cefoxitin and Cefuroxime: A Tale of Two Antibiotics

This study, like a desert caravan venturing into unknown territory, explored the side effects of two antibiotics, cefoxitin and cefuroxime, during intravenous treatment. The researchers discovered that both drugs can lead to thrombophlebitis, a condition that involves inflammation of a vein, and diarrhea. However, the frequency of these side effects differed between the two antibiotics, with cefoxitin showing a slightly higher incidence.

Navigating the Side Effects: Finding a Balance

The study reveals that the severity of diarrhea was associated with decreased renal function and higher dosage of the antibiotics. This is akin to a desert traveler experiencing dehydration due to increased water consumption in harsh conditions. The research suggests that careful monitoring of renal function and dose adjustments might help mitigate these side effects.

Understanding the Risks: A Guide for Patients and Healthcare Providers

This study provides valuable information for patients and healthcare providers alike. By being aware of the potential side effects of cefoxitin and cefuroxime, patients can be more proactive in monitoring their health and communicating with their healthcare providers. Healthcare providers can use this information to make informed decisions about antibiotic selection and dosage, ensuring patient safety and minimizing potential risks.

Dr. Camel's Conclusion

This study highlights the importance of understanding the potential side effects of medications, even those commonly used. By carefully considering individual factors such as renal function and adjusting treatment accordingly, we can navigate the desert of potential side effects and ensure the best possible outcomes for patients.
Date :
  1. Date Completed 1980-04-23
  2. Date Revised 2019-08-23
Further Info :

Pubmed ID

531523

DOI: Digital Object Identifier

10.3109/inf.1979.11.issue-4.12

Related Literature

Article Analysis
・Side Effects of cefoxitin injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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