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Effectiveness of bedtime dosing of benzodiazepines: a placebo-controlled comparison of halazepam and clorazepate.

Author: AdenG C, O'HairD E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Both halazepam and clorazepate were effective in treating anxiety, with halazepam showing greater improvement than clorazepate. Both drugs were well-tolerated, with no serious side effects.
Paper Details　
Original Abstract of the Article :
The efficacy of halazepam and clorazepate were studied in a double-blind placebo-controlled trial. Sixty-four patients with symptoms of anxiety were treated single-blind with placebo for one week; at the end of the week, all patients scored 18 or higher on the Hamilton Anxiety Scale and were entered...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6109568

データ提供：米国国立医学図書館（NLM）

Anxiety: A Desert of Unease

Anxiety, like a persistent desert wind, can create a sense of unease and restlessness. This study explores the effectiveness of two benzodiazepines, halazepam and clorazepate, in reducing anxiety. The researchers conducted a double-blind, placebo-controlled trial to compare the efficacy of these medications in managing anxiety symptoms.

Benzodiazepines: A Potential Oasis for Anxiety

The study found that both halazepam and clorazepate, when administered in a single bedtime dose, were safe and effective in reducing anxiety symptoms. Patients treated with both medications experienced a significant improvement in anxiety scores compared to placebo. These findings suggest that benzodiazepines may offer a valuable option for managing anxiety, particularly when administered at bedtime to minimize daytime sedation.

Managing Anxiety: A Desert Oasis of Calm

Anxiety can be a challenging condition, affecting both mental and physical well-being. It is important to consult with a healthcare professional for proper diagnosis and treatment. While benzodiazepines may offer temporary relief from anxiety symptoms, it is crucial to explore a comprehensive approach to managing anxiety, including lifestyle changes, cognitive-behavioral therapy, and other therapeutic interventions. Remember, finding the right path to calmness and peace of mind can be a transformative journey, allowing you to navigate the desert of life with greater resilience and serenity.

Dr.Camel's Conclusion

The study on the effectiveness of halazepam and clorazepate in reducing anxiety provides valuable insights into the management of this common condition. The findings suggest that benzodiazepines, particularly when administered at bedtime, may offer a safe and effective option for reducing anxiety symptoms. However, it is essential to consult with a healthcare professional for personalized treatment plans and to explore a comprehensive approach to managing anxiety, including lifestyle changes and therapeutic interventions. Remember, like a camel seeking a refreshing oasis in the vast desert, finding the right path to mental peace and well-being is a journey worth pursuing.

Date :
  1. Date Completed 1981-04-24
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

6109568

DOI: Digital Object Identifier

6109568

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PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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