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Ranitidine in the treatment of acute upper gastrointestinal haemorrhage--a comparative study. Preliminary report.

Author: GibińskiK, GórkaZ, NowakA, NowakowskaE, RudzkiJ, SadlińskiC

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study of 50 patients with acute gastrointestinal bleeding found that ranitidine treatment was more effective than standard conservative therapy, particularly in patients with gastric ulcers. Ranitidine reduced the need for blood transfusions and led to better endoscopic findings after treatment. The study suggests that ranitidine may be a beneficial addition to the management of acute gastrointestinal bleeding, especially in patients with gastric ulcers.
Paper Details　
Original Abstract of the Article :
50 patients with acute gastrointestinal bleeding (GIB) were randomly allocated to treatment with i.v. Ranitidine 50 mg b.d., or to a standard conservative therapy. When possible i.v. administration was replaced by oral ranitidine 150 mg b.d. for a total of up to 10 days. Three subgroups included gas...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6124495

データ提供：米国国立医学図書館（NLM）

Ranitidine: A Potential Treatment for Acute Upper Gastrointestinal Haemorrhage?

Acute gastrointestinal bleeding (GIB) is a serious medical condition that can lead to significant morbidity and mortality. This study investigates the effectiveness of ranitidine in the treatment of acute GIB. The researchers conducted a comparative study involving 50 patients with acute GIB, randomly assigned to receive either intravenous ranitidine or standard conservative therapy. The results suggest that ranitidine, particularly in patients with gastric ulcers, was superior to standard treatment in reducing the need for blood replacement and achieving a favorable endoscopic outcome. The study offers promising evidence for the potential benefits of ranitidine in managing acute GIB.

A Potential Advantage for Gastric Ulcers: Ranitidine's Role in GIB Treatment

This study provides evidence for the potential benefits of ranitidine in treating acute GIB, particularly in patients with gastric ulcers. The findings suggest that ranitidine may be superior to standard treatment in reducing the need for blood replacement and achieving a favorable endoscopic outcome. This research underscores the importance of considering ranitidine as a potential treatment option for patients with acute GIB, especially those with gastric ulcers.

Protecting the Digestive Tract: Managing Gastrointestinal Bleeding

This study highlights the importance of effective management strategies for acute GIB, a potentially life-threatening condition. The research suggests that ranitidine may offer a valuable treatment option, particularly in patients with gastric ulcers. The study encourages further investigations into the optimal use of ranitidine and its potential benefits in various types of GIB.

Dr.Camel's Conclusion

This study provides encouraging evidence for the potential benefits of ranitidine in treating acute GIB, especially in patients with gastric ulcers. The findings highlight the importance of considering ranitidine as a potential treatment option and encourage further research into its efficacy and optimal use in managing this serious condition.

Date :
  1. Date Completed 1982-09-10
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6124495

DOI: Digital Object Identifier

6124495

Related Literature

Article Analysis
・Effective treatment of gastrointestinal bleeding
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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