Paper Details

  1. Home
  2. Paper Details

A radiotherapeutic clinical trial of twice per week vs. five times per week in oral cancer.

Author: AgarwalY C, EdoliyaT N, HandaK, PandeyR P, SinhaN

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study of 250 patients with oral cancer compared the effectiveness of daily radiation therapy to twice-weekly radiation therapy. Daily radiation therapy resulted in significantly better tumor regression, acute and late side effects, and tumor control at one year, particularly for patients receiving radical treatment. While daily radiation therapy was still preferable for palliative treatment, the difference in outcomes was less pronounced. The study concludes that twice-weekly radiation therapy may be a suitable alternative only for palliative treatment of advanced oral cancer.
Paper Details　
Original Abstract of the Article :
135 cases of oral cancer have been treated by two fractions per week, and the results are compared with 115 approximately identical cases treated by conventional five days a week schedule with other parameters being identical. Radical irradiation was done by 6000 and 6500 rd in 6--6 1/2 weeks (NSD 1...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/6159698

データ提供：米国国立医学図書館（NLM）

Twice a Week vs. Five Times a Week: Exploring Radiotherapy Regimes for Oral Cancer

This research investigates the effectiveness of two different [radiotherapy] regimens for treating [oral cancer]. The authors compare the outcomes of [twice-a-week] and [five-times-a-week] radiotherapy schedules, analyzing factors like [tumor regression], [acute and late reactions], and [tumor control]. The study reveals that [daily treatment] generally leads to better [tumor regression] and [tumor control] for [radical cure] cases, while [twice-a-week] treatment may be a suitable alternative for [palliative care] in advanced cases.

Radiotherapy Regimens: A Balancing Act Between Effectiveness and Convenience

The study highlights the importance of [individualized treatment] in [oral cancer] management. It's like navigating a desert landscape, where the optimal path may vary depending on the terrain. The authors provide valuable insights into the potential benefits and drawbacks of different [radiotherapy] regimens, offering guidance for clinicians to tailor treatment plans based on the specific needs of the patient. This knowledge can lead to improved outcomes and a better experience for those battling [oral cancer].

Considering the Individual Needs of the Patient

The study emphasizes the need for careful consideration of [radiotherapy] regimens for [oral cancer] patients, taking into account factors like [tumor stage], [patient health], and [treatment goals]. It's like choosing the right tools for a specific task in the desert. The authors' findings highlight the importance of [informed decision-making] in [radiotherapy] treatment, ensuring that patients receive the most effective and appropriate care for their individual needs.

Dr.Camel's Conclusion

This study delves into the world of [oral cancer] treatment, highlighting the importance of [individualized therapy] and careful consideration of [radiotherapy] regimens. The authors' findings provide valuable insights into the effectiveness of different treatment schedules, allowing for more informed decision-making in the management of this complex disease. This research underscores the ongoing quest for finding the most effective and efficient treatments for [oral cancer] patients, a journey that continues to evolve with new discoveries and advancements.

Date :
  1. Date Completed 1981-01-26
  2. Date Revised 2006-09-18
Further Info :

Pubmed ID

6159698

DOI: Digital Object Identifier

6159698

Related Literature

Article Analysis
・Effective treatment of radiation therapy
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.