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Comparative trial of treatment with Prioderm lotion and Kwellada shampoo in children with head lice.

Author: HugginsD R, LerouxS J, MathiasR G, ProctorE M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study of 62 children with head lice compared Prioderm (malathion) lotion to Kwellada (lindane) shampoo. Both treatments effectively killed lice immediately, but both also showed some limited ability to kill lice eggs. Prioderm had a slightly higher initial effectiveness (93% vs. 88% for Kwellada), but this difference may not be significant due to the small sample size. Both treatments were well-tolerated, with no side effects reported. The study recommends two treatments with the same pediculicides, spaced 7 days apart, to ensure complete eradication of both lice and eggs.
Paper Details　
Original Abstract of the Article :
The safety and efficacy of treatment with a new pediculicide lotion, Prioderm (0.5% malathion in isopropanol), were compared with those of treatment with Kwellada (1% lindane) shampoo in a randomized trial of children with head lice. The children's scalps were examined for live lice immediately, 7 d...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876102/

データ提供：米国国立医学図書館（NLM）

Head Lice Treatment: A Comparative Study of Prioderm and Kwellada

Head lice infestations are a common and annoying problem, especially among children. This study investigates the effectiveness of two different pediculicide treatments, Prioderm and Kwellada, in eliminating head lice. The authors conducted a randomized trial to compare the efficacy and safety of these two treatments.

A Two-Pronged Approach: Comparing Pediculicide Effectiveness

The research found that both Prioderm and Kwellada were effective in eliminating live lice immediately after treatment. However, both treatments exhibited incomplete ovicidal activity, leading to some re-infestations after a few weeks. It's like trying to clear a desert path of sand – some sand may remain, requiring additional efforts to fully clear the path.

A Lesson in Persistence: Preventing Re-infestations

The authors recommend using two treatments with the same pediculicide, about 7 days apart, to ensure complete elimination of head lice and their eggs. It's like clearing the path of sand twice to ensure a smooth journey. Understanding these nuances can help us effectively combat head lice infestations.

Dr.Camel's Conclusion

This study provides valuable insights into the effectiveness and limitations of different head lice treatments. It underscores the importance of choosing the right treatment and following proper application instructions to ensure complete eradication of head lice. Like navigating a desert, where preparation and persistence are key, understanding the nuances of head lice treatment can lead to a successful and itch-free journey.

Date :
  1. Date Completed 1984-03-20
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

6198057

DOI: Digital Object Identifier

PMC1876102

Related Literature

Article Analysis
・Side Effects of lindane
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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