Treatment of onychomycosis by ODT therapy with 20% urea ointment and 2% tolnaftate ointment.

Author: AsaiY, HamadaT, IshiiM

Paper Details 
Original Abstract of the Article :
20 patients with distal onychomycosis were given daily application of an ointment containing 2% tolnaftate and an ointment containing 20% urea under ODT. Following this, 17 of 20 patients developed onychomalacia and seven of these developed onycholysis 1 or 2 weeks later. The separated nails were cu...See full text at original site
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引用元:
https://doi.org/10.1159/000249796

データ提供:米国国立医学図書館(NLM)

Treating Onychomycosis: A New Oasis in the Desert of Nail Infections

Imagine a desert of nails, where the fungal infection onychomycosis can leave individuals feeling frustrated and uncomfortable. This study explored a new treatment approach for onychomycosis, using a combination of 20% urea ointment and 2% tolnaftate ointment under occlusion therapy (ODT), a technique that involves covering the treated area with a bandage to increase penetration of the medication.

A Promising Approach to Onychomycosis Treatment

The study showed that ODT with urea and tolnaftate was effective in treating onychomycosis in a significant proportion of patients. The treatment led to onychomalacia, a softening of the nail, and onycholysis, a separation of the nail from the nail bed, in most patients. These findings suggest that the treatment successfully targeted the infected nails, leading to their eventual shedding and replacement with healthy new nails.

Finding Relief from Nail Infections: A New Avenue for Treatment

The results of this study provide a glimmer of hope for individuals struggling with onychomycosis, offering a new and potentially effective treatment option. However, the authors acknowledge that the treatment was not effective for all patients and that further research is needed to optimize the treatment regimen and identify potential side effects.

Dr. Camel's Conclusion

This study, like a desert oasis providing respite from the harsh elements, offers a new avenue for treating onychomycosis. The combination of urea and tolnaftate under ODT appears to be a promising approach, but further research is needed to solidify its efficacy and safety. For those struggling with nail infections, this study provides a glimmer of hope for finding a treatment that can restore healthy nails.

Date :
  1. Date Completed 1984-02-14
  2. Date Revised 2019-09-04
Further Info :

Pubmed ID

6228447

DOI: Digital Object Identifier

10.1159/000249796

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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