Prevention of osteonecrosis following renal transplantation by using vitamin D2 (ergocalciferol).

Author: GrossmannI, MebelM, MrochenH, ScholzD, ScholzeJ, TöpelmannI

Paper Details 
Original Abstract of the Article :
Osteonecrosis is a frequently disabling complication of renal transplantation. Thirty-one of 244 patients (12.7%), who received cadaver renal transplants from 1968 to 1978 developed an osteonecrosis. An analysis of 14 possible risk factors suggested that only the following were significantly more fr...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/6361747

データ提供:米国国立医学図書館(NLM)

Preventing Osteonecrosis After Renal Transplantation: A Desert Oasis of Vitamin D

The desert of kidney disease can be harsh and unforgiving, with complications like osteonecrosis lurking in the shadows. Osteonecrosis, a condition where bone tissue dies, is a potentially debilitating complication of renal transplantation. Like a wise desert nomad seeking a precious resource, this study investigated the role of vitamin D in preventing this complication.

The researchers analyzed data from 244 patients who underwent renal transplantation. They identified several risk factors for osteonecrosis, including high prednisolone doses and high creatinine levels. However, they observed a significant decrease in osteonecrosis rates in patients who received prophylactic vitamin D treatment. This finding, like discovering a hidden oasis in the desert, suggests a powerful role for vitamin D in protecting bone health after transplantation.

Vitamin D: A Beacon in the Desert of Kidney Disease

The study found that vitamin D supplementation significantly reduced the incidence of osteonecrosis, delaying its onset by an average of one year. This finding, like a beacon guiding travelers through the night, highlights the potential of vitamin D in improving outcomes for patients with kidney disease.

A Desert Oasis of Health: The Importance of Vitamin D

The study underscores the importance of maintaining adequate vitamin D levels, especially in individuals with kidney disease. Like a camel storing water for a long journey, ensuring sufficient vitamin D levels can help prevent complications and promote overall health.

Dr. Camel's Conclusion

This study sheds light on the crucial role of vitamin D in preventing osteonecrosis after renal transplantation. It serves as a reminder that even in the seemingly unforgiving desert of kidney disease, there are opportunities to promote health and well-being. By embracing the power of vitamin D, we can navigate the challenges of kidney disease with greater confidence and hope.

Date :
  1. Date Completed 1984-02-24
  2. Date Revised 2008-02-21
Further Info :

Pubmed ID

6361747

DOI: Digital Object Identifier

6361747

Related Literature

SNS
PICO Info
in preparation
Languages

English

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