Meclofenamate treatment of recurrent idiopathic nephrotic syndrome with focal segmental glomerulosclerosis after renal transplantation.

Author: FrohnertP P, HolleyK E, SterioffS, TorresV E, VelosaJ A, ZinckeH

Paper Details 
Original Abstract of the Article :
Recurrent corticosteroid-resistant nephrotic syndrome with focal segmental glomerulosclerosis (FSGS) caused the failure of a first renal allograft in a 41-year-old man. Recurrence of the nephrotic syndrome in the second renal allograft was successfully controlled by the administration of meclofenama...See full text at original site
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引用元:
https://doi.org/10.1016/s0025-6196(12)60765-4

データ提供:米国国立医学図書館(NLM)

Meclofenamate: A Potential Treatment for Recurrent Nephrotic Syndrome

Recurrent nephrotic syndrome, a kidney disorder characterized by protein leakage in the urine, can significantly impact kidney function and overall health. This article explores the use of meclofenamate, a nonsteroidal anti-inflammatory drug (NSAID), as a treatment option for recurrent nephrotic syndrome with focal segmental glomerulosclerosis (FSGS) after renal transplantation.

A Promising Approach for Managing Recurrent Nephrotic Syndrome

The article describes a case study of a patient who experienced recurrent corticosteroid-resistant nephrotic syndrome with FSGS after receiving a second kidney transplant. The patient's nephrotic syndrome was successfully controlled with meclofenamate, and his kidney function remained stable for 2.5 years. This case report suggests that meclofenamate might be a beneficial treatment option for some patients with corticosteroid-resistant nephrotic syndrome and FSGS.

Navigating the Challenges of Kidney Disease

While this case report is promising, further research is needed to confirm the efficacy of meclofenamate in treating recurrent nephrotic syndrome with FSGS. It is crucial to consider the potential side effects of NSAIDs and to carefully monitor patients receiving meclofenamate. This article underscores the ongoing challenges in managing kidney disease and the need for continued research to develop safe and effective treatment options.

Dr. Camel's Conclusion

The journey of kidney disease can be long and arduous, like a camel crossing a vast and unforgiving desert. This case report, like a hidden oasis, offers a glimmer of hope for patients with recurrent nephrotic syndrome. While further research is needed to confirm the effectiveness of meclofenamate, this study highlights the importance of exploring new treatment options and seeking solutions that improve the lives of those affected by kidney disease.

Date :
  1. Date Completed 1984-05-02
  2. Date Revised 2019-05-16
Further Info :

Pubmed ID

6369011

DOI: Digital Object Identifier

10.1016/s0025-6196(12)60765-4

Related Literature

SNS
PICO Info
in preparation
Languages

English

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