Glipizide: an overview.

Author: ShumanC R

Paper Details 
Original Abstract of the Article :
This is a brief summary of the extensive clinical experience with glipizide in the treatment of noninsulin-dependent diabetes mellitus. The data demonstrate that this agent, one of the newest oral hypoglycemics, is an effective and safe compound with unique properties. Among its other qualities, it ...See full text at original site
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引用元:
https://doi.org/10.1016/0002-9343(83)90254-1

データ提供:米国国立医学図書館(NLM)

Glipizide: A New Hope for Non-Insulin Dependent Diabetes

The field of diabetes treatment is a vast and ever-evolving desert, much like the one I call home. This research, like a refreshing oasis, presents glipizide, a new oral hypoglycemic agent, as a potential solution for those struggling with non-insulin dependent diabetes mellitus (NIDDM). It delves into the unique properties of this drug, using clinical experience as its compass to guide us through the complexities of NIDDM management. The authors meticulously analyze the data, revealing that glipizide is effective and safe, offering a glimmer of hope in the fight against this chronic condition.

Glipizide's Multifaceted Approach to NIDDM

This research, like a skilled desert navigator, maps out the intricate mechanisms by which glipizide works. It demonstrates that this compound not only stimulates insulin secretion but also enhances insulin action through extrapancreatic effects. This dual action is akin to a desert explorer utilizing both camels and oases to navigate the vast terrain.

The Importance of Glycemic Control

Managing blood glucose levels is crucial in the treatment of NIDDM. Glipizide, like a sturdy camel, helps to maintain this delicate balance. The research shows that it effectively lowers plasma glucose levels, even with its short half-life, and can be used in conjunction with insulin to achieve optimal glycemic control. This is akin to a desert explorer utilizing a combination of resources – water and shade – to conquer the harsh environment.

Dr. Camel's Conclusion

Glipizide holds great promise in the treatment of NIDDM. Its effectiveness, safety, and unique properties offer a beacon of hope for those navigating the challenging desert of diabetes management. It's like discovering a new oasis in the middle of a vast desert. I am hopeful that this research will lead to improved outcomes for those living with NIDDM.

Date :
  1. Date Completed 1984-05-11
  2. Date Revised 2019-06-27
Further Info :

Pubmed ID

6369968

DOI: Digital Object Identifier

10.1016/0002-9343(83)90254-1

Related Literature

SNS
PICO Info
in preparation
Languages

English

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