Budesonide. A preliminary review of its pharmacodynamic properties and therapeutic efficacy in asthma and rhinitis.

Author: ClissoldS P, HeelR C

Paper Details 
Original Abstract of the Article :
Budesonide is a non-halogenated glucocorticosteroid which has been shown to possess a high ratio of topical to systemic activity compared with a number of reference corticosteroids such as beclomethasone dipropionate, flunisolide, and triamcinolone acetonide. It appears to undergo extensive first-pa...See full text at original site
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引用元:
https://doi.org/10.2165/00003495-198428060-00001

データ提供:米国国立医学図書館(NLM)

Budesonide: A Powerful Corticosteroid for Asthma and Rhinitis

Asthma and rhinitis are common respiratory conditions that can significantly affect quality of life. This study reviewed the pharmacodynamic properties and therapeutic efficacy of budesonide, a non-halogenated glucocorticosteroid, in managing these conditions. The review highlighted the high topical-to-systemic activity ratio of budesonide, making it an effective treatment option with limited systemic side effects. Numerous clinical trials demonstrated that inhaled budesonide was comparable to other inhaled corticosteroids in controlling asthma symptoms. In some cases, high doses of inhaled budesonide even outperformed oral prednisone in managing severe asthma. Intranasal budesonide was also found to be effective in relieving nasal symptoms in patients with allergic and vasomotor rhinitis.

A New Era in Respiratory Treatment

This review provides a comprehensive overview of the effectiveness of budesonide in managing asthma and rhinitis. The findings suggest that budesonide is a valuable addition to the respiratory therapist's toolkit, offering an effective and potentially safer alternative to other corticosteroids. The high topical-to-systemic activity ratio of budesonide is particularly important, as it minimizes the risk of systemic side effects, a significant advantage for long-term treatment.

Navigating the Desert of Respiratory Conditions

The research on budesonide is a reminder that finding effective and safe treatments for respiratory conditions can be a challenging journey. It's like navigating a vast desert, searching for the right medication to alleviate symptoms and improve quality of life. This review provides a valuable resource for understanding the efficacy and safety profile of budesonide, helping to guide treatment decisions and improve patient care.

Dr.Camel's Conclusion

This review highlights the importance of research in developing innovative treatments for respiratory conditions. It's like discovering a hidden spring of healing in the desert of respiratory ailments. Budesonide's effectiveness and safety profile make it a promising treatment option for asthma and rhinitis, potentially improving the lives of countless individuals.

Date :
  1. Date Completed 1985-02-22
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

6394263

DOI: Digital Object Identifier

10.2165/00003495-198428060-00001

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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