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Original Abstract of the Article :
Budesonide is a non-halogenated glucocorticosteroid which has been shown to possess a high ratio of topical to systemic activity compared with a number of reference corticosteroids such as beclomethasone dipropionate, flunisolide, and triamcinolone acetonide. It appears to undergo extensive first-pa...See full text at original site
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引用元:
https://doi.org/10.2165/00003495-198428060-00001
データ提供:米国国立医学図書館(NLM)
Budesonide: A Powerful Corticosteroid for Asthma and Rhinitis
Asthma and rhinitis are common respiratory conditions that can significantly affect quality of life. This study reviewed the pharmacodynamic properties and therapeutic efficacy of budesonide, a non-halogenated glucocorticosteroid, in managing these conditions. The review highlighted the high topical-to-systemic activity ratio of budesonide, making it an effective treatment option with limited systemic side effects. Numerous clinical trials demonstrated that inhaled budesonide was comparable to other inhaled corticosteroids in controlling asthma symptoms. In some cases, high doses of inhaled budesonide even outperformed oral prednisone in managing severe asthma. Intranasal budesonide was also found to be effective in relieving nasal symptoms in patients with allergic and vasomotor rhinitis.
A New Era in Respiratory Treatment
This review provides a comprehensive overview of the effectiveness of budesonide in managing asthma and rhinitis. The findings suggest that budesonide is a valuable addition to the respiratory therapist's toolkit, offering an effective and potentially safer alternative to other corticosteroids. The high topical-to-systemic activity ratio of budesonide is particularly important, as it minimizes the risk of systemic side effects, a significant advantage for long-term treatment.
Navigating the Desert of Respiratory Conditions
The research on budesonide is a reminder that finding effective and safe treatments for respiratory conditions can be a challenging journey. It's like navigating a vast desert, searching for the right medication to alleviate symptoms and improve quality of life. This review provides a valuable resource for understanding the efficacy and safety profile of budesonide, helping to guide treatment decisions and improve patient care.
Dr.Camel's Conclusion
This review highlights the importance of research in developing innovative treatments for respiratory conditions. It's like discovering a hidden spring of healing in the desert of respiratory ailments. Budesonide's effectiveness and safety profile make it a promising treatment option for asthma and rhinitis, potentially improving the lives of countless individuals.
Date :
- Date Completed 1985-02-22
- Date Revised 2018-11-13
Further Info :
Related Literature
English
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