Efficacy and safety of nabumetone in long-term treatment of osteoarthritis.

Author: PintensH, VerbruggenL A

Paper Details 
Original Abstract of the Article :
Nabumetone, belonging to a new class of anti-inflammatory drugs, was administered to 9 patients suffering from radiologically-confirmed osteoarthritis of one or more of the following articulations: knees, hips, cervical and lumbar spine. A single nightly dose of 1 g was given for at least one year, ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/6396271

データ提供:米国国立医学図書館(NLM)

Nabumetone: A Promising Long-Term Treatment for Osteoarthritis

Osteoarthritis (OA) is a common condition that affects millions of people worldwide. This study explores the efficacy and safety of nabumetone, a nonsteroidal anti-inflammatory drug (NSAID), for long-term management of OA. The researchers evaluated the effects of nabumetone in 9 patients with radiologically confirmed OA of various joints, including knees, hips, and spine.

The researchers found that nabumetone was generally effective in improving articular mobility, reducing night pain, and alleviating pain during activity. They also observed no significant adverse effects on hematological parameters, renal function, or liver function. While some patients reported gastrointestinal side effects, these did not lead to discontinuation of treatment. The researchers concluded that nabumetone shows promise as a safe and effective long-term treatment for OA.

Navigating the Desert of Osteoarthritis

This study provides valuable insights into the potential of nabumetone for managing OA. The researchers' findings offer hope for individuals seeking long-term pain relief and improved mobility.

Living with Osteoarthritis

The researchers' findings highlight the importance of continued research and development of effective and safe treatments for OA.

Dr. Camel's Conclusion

This study demonstrates the potential of nabumetone as a safe and effective long-term treatment for osteoarthritis, offering a promising option for individuals seeking to manage pain and improve mobility. The researchers' findings encourage further investigation into nabumetone's long-term efficacy and safety profile.

Date :
  1. Date Completed 1985-04-08
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

6396271

DOI: Digital Object Identifier

6396271

Related Literature

SNS
PICO Info
in preparation
Languages

English

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