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A multicenter evaluation of bupropion versus placebo in hospitalized depressed patients.

Author: BrodieH K, FabreL F, GarverD, ZungW W

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

Bupropion was effective in treating depression in 75 hospitalized patients. It was particularly effective in older patients and those with severe illness. Bupropion had minimal side effects, with no significant cardiovascular or lab findings.
Paper Details　
Original Abstract of the Article :
Bupropion, a new antidepressant with a novel structure and neurochemical profile, was compared to placebo in a three-center evaluation. Seventy-five depressed inpatients, 48 on bupropion and 27 on placebo, participated for up to 28 days. At dosages of 300-600 mg/day, bupropion was significantly more...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://pubmed.ncbi.nlm.nih.gov/6406472

データ提供：米国国立医学図書館（NLM）

A Multicenter Evaluation of Bupropion versus Placebo in Hospitalized Depressed Patients

The journey through depression can feel like traversing a vast and unforgiving desert. This study delves into the effectiveness of bupropion, an antidepressant, for individuals experiencing depression. The researchers conducted a multi-center study to compare the effectiveness of bupropion with placebo in hospitalized patients with depression. This study used a randomized controlled trial design to compare the effects of bupropion with placebo in a group of hospitalized patients with depression. The results showed that bupropion was significantly more effective than placebo in reducing depressive and anxious symptoms.

Bupropion: A Potential Oasis in the Desert of Depression

The study's findings suggest that bupropion can be an effective treatment option for hospitalized patients with depression. This discovery offers a potential ray of hope in the challenging landscape of mental health. Imagine finding a hidden oasis in the desert, providing respite and rejuvenation – bupropion could offer a similar lifeline for individuals battling depression.

Finding Your Way Out: Hope for Depressed Individuals

This research provides valuable information for healthcare professionals and individuals seeking treatment for depression. The study highlights the potential benefits of bupropion in managing depression, offering hope for a brighter future. Remember, even in the most desolate desert, a beacon of hope can guide you towards a path of recovery. Consult with a mental health professional to explore all available treatment options and find the most effective path to recovery.

Dr. Camel's Conclusion

This research provides valuable insights into the effectiveness of bupropion for treating depression. It's like finding a hidden oasis in a vast desert, offering hope and relief for individuals struggling with this challenging condition. The findings suggest that bupropion could be a valuable tool in the fight against depression, offering a potential path to recovery and well-being.

Date :
  1. Date Completed 1983-07-08
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6406472

DOI: Digital Object Identifier

6406472

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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