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Fixed combination mezlocillin/oxacillin injected intramuscularly. Comparative study of local tolerability compared with ampicillin and determination of effectiveness and tolerability in the treatment of surgical and urinary tract infections.

Author: BelliL, FreylejerA, GandolfoS, GinesínL M, RíosJ F

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Mezlocillin/oxacillin combination was found to be well-tolerated and effective in treating wound infections, biliary tract infections, urinary tract infections, appendicitis, and peritonitis. 19 out of 20 patients were clinically cured after 7 days of treatment with the combination. The only side effect reported was a generalized exanthema in one patient.
Paper Details　
Original Abstract of the Article :
The results of two studies on tolerability and efficacy of mezlocillin/oxacillin are reported. The pain caused by i.m. injection of 1 g (20% solution) of the fixed antibiotics combination mezlocillin/oxacillin is compared with that caused by 1 g ampicillin. The injection volume was 5 ml. The statist...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6449205

データ提供：米国国立医学図書館（NLM）

Evaluating the Efficacy and Tolerability of Fixed Combination Mezlocillin/Oxacillin

This study investigates the effectiveness and tolerability of a fixed combination of [treatment method] for treating various infections. The researchers conducted two studies to evaluate the local tolerability, efficacy, and overall tolerability of [treatment method] in comparison to ampicillin. They found that [treatment method] was well-tolerated, with a lower incidence of pain upon injection compared to ampicillin. Additionally, [treatment method] was effective in treating wound infections, biliary tract infections, urinary tract infections, appendicitis, and peritonitis.

A Well-Tolerated and Effective Treatment Option

The study's findings suggest that [treatment method] could be a valuable treatment option for various infections. The researchers found that [key findings], highlighting the potential benefits of this fixed combination therapy.

Navigating the Desert of Infections

This study emphasizes the importance of choosing appropriate treatment options for different types of infections. The findings suggest that [treatment method] could be a viable option for many patients. However, it's crucial to consult with a healthcare professional to determine the most effective and safe treatment plan based on individual needs.

Dr.Camel's Conclusion

This study provides evidence that [treatment method] is a well-tolerated and effective treatment option for a variety of infections. This is a valuable addition to the arsenal of antibiotics available to healthcare professionals. As we navigate the desert of infections, having a range of safe and effective treatment options is crucial for ensuring optimal patient outcomes.

Date :
  1. Date Completed 1981-01-29
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6449205

DOI: Digital Object Identifier

6449205

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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