Mevinolin plus colestipol in therapy for severe heterozygous familial hypercholesterolemia.

Author: IllingworthD R

Paper Details 
Original Abstract of the Article :
Twelve patients with severe heterozygous familial hypercholesterolemia, in whom other hypolipidemic drug therapy had failed to reduce serum cholesterol levels to less than 300 mg/dL, were sequentially treated with mevinolin (a specific inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, th...See full text at original site
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引用元:
https://doi.org/10.7326/0003-4819-101-5-598

データ提供:米国国立医学図書館(NLM)

Treating Severe Familial Hypercholesterolemia: A Quest for Effective Therapies

Familial hypercholesterolemia (FH) is a challenging condition, like a relentless desert wind that carries a heavy burden. This study investigates the use of mevinolin and colestipol, two medications that can help lower cholesterol levels. The authors found that this combination, like a well-stocked caravan, is effective in reducing cholesterol levels, particularly in patients with severe FH who have not responded to other therapies. It's a promising solution, like finding a hidden oasis in the desert, offering relief from a challenging condition.

Navigating the Desert of High Cholesterol

The study demonstrates that combined therapy with mevinolin and colestipol is effective in lowering cholesterol levels in patients with severe FH. This is like finding a reliable source of water in a dry desert, providing a lasting solution for a persistent problem. The researchers found that this approach significantly reduced LDL cholesterol levels, offering a crucial step toward managing this challenging condition.

Managing Cholesterol Levels: A Crucial Step Toward Better Health

The study's findings highlight the importance of finding effective treatments for FH, like finding a path through a treacherous desert landscape. By successfully reducing cholesterol levels, these medications can help prevent heart disease and improve overall health. This research is a reminder that even in the face of challenging conditions, there is hope for better health and a brighter future.

Dr.Camel's Conclusion

This study provides a valuable insight into the management of severe FH, demonstrating the effectiveness of combined therapy with mevinolin and colestipol. It's like finding a new oasis in the desert of high cholesterol, offering a promising avenue for improved health and wellbeing. This research is a testament to the ongoing quest for better treatments for challenging medical conditions.

Date :
  1. Date Completed 1984-11-14
  2. Date Revised 2019-06-19
Further Info :

Pubmed ID

6567462

DOI: Digital Object Identifier

10.7326/0003-4819-101-5-598

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PICO Info
in preparation
Languages

English

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