Effects of amoxapine on serotonin uptake in human blood platelets of depressed patients and normal controls.

Author: AroraR C, MeltzerH Y

Paper Details 
Original Abstract of the Article :
The effect of amoxapine and imipramine on the serotonin (5-HT) uptake of blood platelets from depressed patients and normal controls was studied ex vivo or in vitro, respectively. Amoxapine was approximately one-tenth as potent as imipramine in inhibiting 5-HT uptake in blood platelets from normal c...See full text at original site
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引用元:
https://doi.org/10.1016/0165-1781(83)90086-0

データ提供:米国国立医学図書館(NLM)

Amoxapine: Uncovering the Desert's Hidden Pathways in Depression

Depression, a complex and often debilitating condition, can feel like a vast and desolate desert, leaving individuals lost and without hope. This research, like a meticulous desert explorer, investigates the effects of amoxapine, a medication used to treat depression, on serotonin uptake in the brain, uncovering hidden pathways in the desert of depression.

The study, like a careful analysis of desert soil samples, examines the impact of amoxapine on serotonin uptake in blood platelets, offering insights into its potential mechanisms of action. The researchers find that amoxapine, though less potent than imipramine, another antidepressant, demonstrates a distinct effect on serotonin uptake, suggesting unique pathways of action in the brain. This discovery, like a hidden oasis in the desert, reveals new possibilities for understanding and treating depression.

Unveiling the Desert's Secrets

This study underscores the complexity of depression, like a vast and intricate desert landscape. It highlights the importance of understanding the diverse mechanisms of action of antidepressant medications, like navigating the desert's hidden pathways, to develop more effective and personalized treatment approaches.

Finding Relief in the Desert

This research provides valuable insights into the potential of amoxapine as a therapeutic agent for depression, offering hope for a more effective and targeted treatment approach. It underscores the importance of ongoing research to unveil the desert's hidden pathways, leading to greater understanding and relief for those struggling with depression.

Dr.Camel's Conclusion

This research delves into the complex landscape of depression, uncovering the unique effects of amoxapine on serotonin uptake. It highlights the importance of understanding the diverse mechanisms of action of antidepressant medications, like navigating the desert's hidden pathways, to develop more effective and personalized treatment approaches, offering hope for a brighter future in the fight against this debilitating condition.

Date :
  1. Date Completed 1983-10-28
  2. Date Revised 2019-08-25
Further Info :

Pubmed ID

6577482

DOI: Digital Object Identifier

10.1016/0165-1781(83)90086-0

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Languages

English

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