[Potential value of the amoxicillin-clavulanic acid combination in general medicine, gynecology-obstetrics and pediatrics departments].

Author: GrossetJ, JarlierV, Truffot-PernotC

Paper Details 
Original Abstract of the Article :
This study compares the probability of in vitro activity of amoxicillin-clavulanic acid combination (AMOX-CLA) with those of amoxicillin (AMOX), cephalothin (CEPH), cotrimoxazole (COT) and nalidixic acid (NAL) on the 2 003 strains isolated during the first semester of 1983 in 5 wards of medicine (ME...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/6611533

データ提供:米国国立医学図書館(NLM)

Amoxicillin-Clavulanic Acid: A Versatile Weapon Against Infections

Greetings from Dr. Camel, your guide to the intricate world of [antibiotics]. This study delves into the in vitro activity of amoxicillin-clavulanic acid combination (AMOX-CLA) against bacterial strains isolated from various hospital wards. The study compared the effectiveness of AMOX-CLA with other commonly used antibiotics – amoxicillin (AMOX), cephalothin (CEPH), cotrimoxazole (COT), and nalidixic acid (NAL). The findings revealed that AMOX-CLA demonstrated strong activity against a broad range of bacterial strains, particularly those resistant to AMOX alone. This combination proved superior to AMOX in almost all cases, exhibiting comparable efficacy to CEPH, COT, and NAL in specific situations. Moreover, AMOX-CLA showed a higher activity rate than AMOX against urinary strains, strains isolated from the genital tract, and specimens taken at birth.

A Broad Spectrum of Action

The study highlights the effectiveness of AMOX-CLA against a wide range of bacterial strains, especially those resistant to other antibiotics. This versatility makes AMOX-CLA a valuable tool in combating infections, particularly in situations where other antibiotics may be ineffective. It's like having a multi-purpose tool in a desert survival kit – always ready to handle various challenges.

A Safer Choice

This study emphasizes the potential benefits of AMOX-CLA as a safer alternative to some other antibiotics, especially for pregnant women and neonates. Its broader spectrum of activity combined with a favorable safety profile makes it a valuable option for treating infections across a range of populations. It's a beacon of hope in the vast desert of antibiotic resistance, offering a safer path for treatment.

Dr. Camel's Conclusion

The study underscores the value of AMOX-CLA in battling bacterial infections. Its efficacy against a wide range of strains, particularly those resistant to other antibiotics, makes it a valuable tool in the fight against infectious diseases. It's a reminder that in the vast desert of medical research, collaboration and innovation lead to powerful solutions.

Date :
  1. Date Completed 1984-09-19
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

6611533

DOI: Digital Object Identifier

6611533

Related Literature

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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