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Comparisons of the analgesic effects of oral and intramuscular oxymorphone and of intramuscular oxymorphone and morphine in patients with cancer.

Author: BeaverW T, HoudeR W, RogersA, WallensteinS L

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Oral oxymorphone was less potent than intramuscular oxymorphone in treating cancer pain, but had a longer duration of action. Intramuscular oxymorphone was more potent than morphine.
Paper Details　
Original Abstract of the Article :
The relative analgesic potency of oral and intramuscular oxymorphone was evaluated in a double-blind crossover comparison of graded single doses in patients with chronic pain due to cancer. When both duration and intensity of analgesia are considered (total effect), oral oxymorphone was 1/6 as poten...See full text at original site
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引用元：
https://doi.org/10.1177/009127007701700402

データ提供：米国国立医学図書館（NLM）

Oxymorphone: A Camel's Journey Through Pain Relief

The desert of pain can be a harsh and unforgiving landscape, and finding effective pain relief is like discovering a refreshing oasis. This research delves into the world of opioid analgesics, comparing the analgesic effects of oral and intramuscular oxymorphone, and intramuscular oxymorphone and morphine. It's like a camel caravan exploring different paths in the desert, seeking the most comfortable and efficient route to its destination.

A More Comfortable Journey Through the Desert of Pain

The study found that oral oxymorphone was less potent than intramuscular oxymorphone, but with a longer duration of action. It also found that intramuscular oxymorphone was significantly more potent than morphine. This is like finding that one path through the desert is less steep but longer, while another path is steeper but shorter. The researchers concluded that oxymorphone, both oral and intramuscular, was a valuable alternative to morphine in patients with cancer pain, offering comparable pain relief with a similar side effect profile.

Navigating the Desert with Caution

While this research offers promising findings, it's essential to remember that all medications, even those with fewer side effects, can have risks. It's important to consult with a healthcare professional to determine the best course of action for individual needs. Just as camels adapt to the desert environment, we need to be aware of our individual responses to medication and work with our healthcare providers to find the best possible solutions for our pain management needs.

Dr. Camel's Conclusion

This research is like a map guiding us through the desert of pain. It highlights the potential of oxymorphone as a valuable pain management option, offering a more comfortable and effective journey. As with any medication, it's essential to consult with a healthcare professional to find the best approach for individual needs, ensuring a safe and successful path to relief.

Date :
  1. Date Completed 1977-05-27
  2. Date Revised 2019-08-23
Further Info :

Pubmed ID

66240

DOI: Digital Object Identifier

10.1177/009127007701700402

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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