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Effects of various anthelmintics on larval stages of Nematospiroides dubius (Nematoda).

Author: JacobsonR H, SaylesP C

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Levamisole phosphate effectively reduces worm burdens in mice but can be toxic at higher doses. Ivermectin is highly effective and safe for removing worms. Albendazole, cambendazole, pyrantel pamoate, and fenbendazole are less effective.
Paper Details　
Original Abstract of the Article :
The effects of six anthelmintics on larval stages of Nematospiroides dubius in mice were assessed. Levamisole phosphate, at a dose of 100 mg/kg administered per os 6 days postlarval inoculation (PI), effected greater than 98% reduction in worm burdens. At dose rates one log2 higher, 50% mortality of...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/6674458

データ提供：米国国立医学図書館（NLM）

Fighting Parasitic Worms: A Tale of Anthelmintics

The world of parasites is a fascinating and often challenging one, with these tiny organisms capable of causing significant health problems. This study investigates the effectiveness of various anthelmintics, drugs used to combat parasitic worms, against the larval stages of Nematospiroides dubius, a common parasite in mice. The researchers tested six different anthelmintics, finding that ivermectin emerged as the most effective larvicidal drug due to its high efficacy and minimal toxicity. The study provides valuable insights into the potential use of ivermectin for controlling parasitic infections.

Ivermectin: A Promising Weapon in the Fight Against Parasitic Worms

This research sheds light on the potential of ivermectin as a potent anthelmintic, offering hope for new strategies to combat parasitic infections.

Ivermectin: A Promising Weapon in the Fight Against Parasitic Worms

Think of parasitic worms as pesky desert creatures, wreaking havoc on your health. Ivermectin, like a well-aimed arrow, targets these parasites effectively, offering a potential solution to control their spread. This study is like discovering a new and potent weapon in the fight against these troublesome creatures.

Dr.Camel's Conclusion

This study highlights the crucial role of anthelmintics in combating parasitic infections. The discovery of ivermectin's effectiveness provides a promising avenue for developing new and effective therapies to control these pervasive parasites.

Date :
  1. Date Completed 1984-06-18
  2. Date Revised 2007-11-14
Further Info :

Pubmed ID

6674458

DOI: Digital Object Identifier

6674458

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Languages

English

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