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A comparison of the analgesic effect of oxymorphone by rectal suppository and intramuscular injection in patients with postoperative pain.

Author: BeaverW T, FeiseG A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Rectal oxymorphone was less potent than intramuscular oxymorphone, but provided comparable analgesia to parenteral narcotics. It had a longer duration of action and fewer side effects.
Paper Details　
Original Abstract of the Article :
The relative analgesic potency of oxymorphone by rectal suppository and intramuscular injection was evaluated in a double-blind, twin-crossover comparison of graded single doses in 136 patients with postoperative pain. The time-effect curves of the two routes of administration differed substantially...See full text at original site
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引用元：
https://doi.org/10.1002/j.1552-4604.1977.tb04607.x

データ提供：米国国立医学図書館（NLM）

Comparing Analgesic Effects of Oxymorphone: Rectal vs. Intramuscular

This research investigates the [relative analgesic potency] of [oxymorphone] administered via [rectal suppository and intramuscular injection] in [patients with postoperative pain]. The study employed a [double-blind, twin-crossover comparison] to evaluate the [time-effect curves] of the two routes of administration. The findings suggest that [rectal oxymorphone is less potent but offers a longer duration of action] compared to [intramuscular administration], demonstrating the [feasibility and practicality] of [rectal administration] for [postoperative pain management].

Exploring Alternative Routes: A New Perspective on Analgesia

The study highlights the [importance of considering alternative routes] for [analgesic administration], demonstrating the [efficacy and practicality] of [rectal oxymorphone]. The findings underscore the [need for further research] to [optimize the use of rectal analgesics] and [expand treatment options] for [postoperative pain management].

Navigating the Path to Pain Relief: Exploring Different Avenues

Postoperative pain can be a significant challenge, impacting [recovery time] and [quality of life]. This study explores a [new avenue for analgesia], highlighting the [potential of rectal oxymorphone] in [providing effective and well-tolerated pain relief].

Dr. Camel's Conclusion

Just as a camel navigates a desert, seeking out different sources of nourishment and finding ways to adapt to its surroundings, healthcare providers need to explore different routes for administering analgesia. This study highlights the potential of rectal oxymorphone, offering a new pathway to effective pain management.
Date :
  1. Date Completed 1977-06-30
  2. Date Revised 2019-08-23
Further Info :

Pubmed ID

67128

DOI: Digital Object Identifier

10.1002/j.1552-4604.1977.tb04607.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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