Multicenter evaluation of mepindolol and of mepindolol plus hydrochlorothiazide in essential hypertension.

Author: GalassiA, GinevrinoP, LibrettiA, MasoniA, MorgagniW, RappelliA, TomasiA M

Paper Details 
Original Abstract of the Article :
The effect on systolic (SAP) and diastolic (DAP) arterial blood pressure of 5 mg mepindolol daily vs 12.5 mg hydrochlorothiazide daily vs 5 mg mepindolol plus 12.5 mg hydrochlorothiazide daily was evaluated in this multicenter study. After a 2-week washout period with placebo, 138 patients with mild...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/6757152

データ提供:米国国立医学図書館(NLM)

Mepindolol for Essential Hypertension: A Promising Antihypertensive

Essential hypertension, like a persistent desert heatwave, can strain the body's cardiovascular system. Mepindolol, a beta-blocker with vasodilatory properties, has emerged as a potential treatment for this common condition. This multicenter study evaluates the efficacy and tolerability of mepindolol alone and in combination with hydrochlorothiazide, another antihypertensive medication.

Mepindolol Shows Promise: Effective and Well-Tolerated

The study demonstrated that mepindolol, both alone and in combination with hydrochlorothiazide, effectively lowered blood pressure in patients with mild to moderate essential hypertension. The researchers found that mepindolol was well-tolerated, with minimal side effects. The findings suggest that mepindolol, given as a single daily dose, could be a valuable addition to the therapeutic arsenal for managing essential hypertension.

Expanding Treatment Options: Mepindolol's Potential in Hypertension Management

This research offers a promising new option for patients seeking effective and well-tolerated treatment for essential hypertension. The study's findings encourage further exploration of mepindolol's role in hypertension management, potentially leading to improved patient outcomes and enhanced quality of life for those living with this condition.

Dr. Camel's Conclusion

This research, like a cool breeze in the desert, provides a refreshing perspective on hypertension treatment. The study's findings suggest that mepindolol, with its efficacy and tolerability, could be a valuable tool for managing this common condition. By expanding the range of treatment options, we can better address the needs of patients seeking effective and well-tolerated solutions for hypertension management, ultimately contributing to improved cardiovascular health and well-being.

Date :
  1. Date Completed 1983-02-14
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6757152

DOI: Digital Object Identifier

6757152

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.