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A controlled long-term study with ergoloid mesylates (Hydergine) in healthy, elderly volunteers: results after three years.
Author: HuberF, KöberleS, SpiegelR
Original Abstract of the Article :
A long-term clinical comparison of the effects of ergoloid mesylates and placebo on 148 healthy elderly volunteers of both sexes was analyzed after three years of study. At that point, 99 subjects (53 receiving ergoloid mesylates and 46, placebo) were still being treated under double-blind condition...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/j.1532-5415.1983.tb02200.x
データ提供:米国国立医学図書館(NLM)
Ergoloid Mesylates: A Long-Term Study in Healthy Elderly Volunteers
Aging is a natural process that can bring about various physical and cognitive changes. This study investigates the potential effects of ergoloid mesylates, a drug used to treat cognitive impairment associated with aging, in healthy elderly volunteers. Researchers conducted a long-term, double-blind study, comparing the effects of ergoloid mesylates to placebo over a three-year period. The study found that ergoloid mesylates were well tolerated and appeared to provide some benefits, including improvements in subjective symptoms, cognitive function, and certain laboratory parameters. However, the study also noted an increase in blood pressure in both treatment groups, suggesting a need for further investigation of potential cardiovascular effects.
The Search for Anti-Aging Interventions
This study contributes to the ongoing search for interventions that can mitigate the effects of aging. The researchers' findings suggest that ergoloid mesylates may offer some benefits for healthy elderly individuals, particularly in terms of cognitive function and subjective well-being. However, the study's findings also highlight the need for further research to better understand the long-term effects of ergoloid mesylates and to ensure their safety and efficacy.
The Importance of Comprehensive Evaluation
This study emphasizes the importance of comprehensive evaluation in assessing the effectiveness and safety of interventions targeting aging. The researchers' findings highlight the need to consider both potential benefits and risks, as well as the long-term effects of interventions. A comprehensive approach to research can help ensure the development of safe and effective interventions to promote healthy aging.
Dr. Camel's Conclusion
This research, like a camel caravan traversing a desert landscape filled with the wisdom of age, provides valuable insights into the potential benefits and risks of ergoloid mesylates in healthy elderly individuals. The study's findings underscore the need for further research to better understand the long-term effects of this drug and to ensure its safe and effective use in promoting healthy aging.
Date :
- Date Completed 1983-10-21
- Date Revised 2019-07-09
Further Info :
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