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Contribution of prednisolone to the primary endocrine treatment of advanced breast cancer.

Author: HaywardJ L, KingR J, KnightR K, MintonM J, RubensR D, SteinerR, StewartJ F, TongD, WinterP J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

The study found that tamoxifen combined with prednisolone was more effective in inducing responses in postmenopausal patients with advanced breast cancer compared to tamoxifen alone. The combination also showed a trend towards longer survival and mitigated hypercalcemia and tumor flare seen with tamoxifen alone.
Paper Details　
Original Abstract of the Article :
Two hundred and four patients with progressive locally advanced or metastatic breast cancer not controllable by local therapy alone, and who had had no prior systemic therapy for advanced disease, were treated by primary endocrine therapy according to menopausal status. Premenopausal patients receiv...See full text at original site
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引用元：
https://doi.org/10.1016/0277-5379(82)90134-1

データ提供：米国国立医学図書館（NLM）

Prednisolone: A Powerful Ally in Breast Cancer Treatment

This study ventures into the complex world of

oncology

and explores the role of prednisolone in treating advanced breast cancer. This research, like a caravan traversing a vast desert, meticulously examines the effectiveness of prednisolone in combination with other endocrine therapies. The researchers found that prednisolone significantly improved response rates and potentially prolonged survival in patients with estrogen receptor-positive tumors. This study offers valuable insights into optimizing treatment strategies for this challenging disease.

Prednisolone's Impact on Treatment Outcomes

This research highlights the significant impact of prednisolone on the effectiveness of endocrine therapy for advanced breast cancer. The results show that prednisolone, like a skilled navigator guiding a caravan through the desert, can significantly improve patient outcomes. This study emphasizes the importance of personalized medicine, tailoring treatment strategies based on individual factors like tumor characteristics. The findings suggest that prednisolone may play a crucial role in improving response rates and potentially enhancing survival in specific patient populations.

A Beacon of Hope for Breast Cancer Patients

This study offers a glimmer of hope for breast cancer patients, highlighting the potential benefits of prednisolone in treating advanced disease. The findings suggest that prednisolone, like a refreshing oasis in the desert, can provide relief from symptoms and potentially improve long-term outcomes. The study underscores the importance of ongoing research to further refine treatment strategies and improve the lives of breast cancer patients.

Dr.Camel's Conclusion

This research provides valuable evidence for the potential benefits of prednisolone in treating advanced breast cancer. The study highlights the importance of personalized medicine and underscores the need for continued research to optimize treatment strategies for this complex disease.

Date :
  1. Date Completed 1983-05-27
  2. Date Revised 2019-09-09
Further Info :

Pubmed ID

6891929

DOI: Digital Object Identifier

10.1016/0277-5379(82)90134-1

Related Literature

Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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