Paper Details

  1. Home
  2. Paper Details

Preliminary clinical trial with a new hypotensive, guanabenz, in a group of hypertensive patients.

Author: De RidderJ H, MarchandiseP

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Guanabenz is effective in controlling blood pressure in 64% of hypertensive patients. The most common side effects are dry mouth and nausea.
Paper Details　
Original Abstract of the Article :
In a small preliminary clinical trial of guanabenz in 16 hypertensives also under treatment with diuretics (hydrochlorothiazide and amiloride), blood pressure was safely and completely controlled in 10 (64%), the criterion for "control" being a reduction to the strict level specified by the Society ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/6970485

データ提供：米国国立医学図書館（NLM）

Guanabenz: A Potential Oasis in the Desert of Hypertension

Hypertension, a silent but dangerous condition, affects millions worldwide. This study explores the potential of guanabenz, a hypotensive agent, in managing hypertension. The research investigated the efficacy and safety of guanabenz in a small group of hypertensive patients already receiving diuretic therapy.

Guanabenz: A Promising Addition to the Arsenal

The study found that guanabenz effectively controlled blood pressure in a significant proportion of patients, demonstrating its potential as an effective treatment option for hypertension. The dosage of guanabenz was adjusted upward until blood pressure normalized or side effects intervened. While some patients discontinued treatment due to side effects, the overall results suggest that guanabenz may offer a valuable addition to the arsenal of hypertension treatment.

Navigating the Desert of Hypertension: A Personalized Approach

This research emphasizes the importance of personalized approaches to managing hypertension, considering individual patient characteristics and potential side effects. The study highlights the need for careful monitoring of blood pressure and for adjusting dosages accordingly. Further research is needed to fully evaluate the long-term efficacy and safety of guanabenz, but this study provides promising insights into its potential as a valuable tool for hypertension management.

Dr. Camel's Conclusion

This research offers a glimpse into the potential of guanabenz as a promising treatment option for hypertension. While further research is needed to fully understand its long-term efficacy and safety, this study suggests that guanabenz may offer a valuable addition to the arsenal of hypertension treatment, particularly in conjunction with diuretic therapy. This research underscores the importance of personalized approaches to managing hypertension, ensuring that patients receive the most effective and well-tolerated care.

Date :
  1. Date Completed 1981-04-24
  2. Date Revised 2017-05-11
Further Info :

Pubmed ID

6970485

DOI: Digital Object Identifier

6970485

Related Literature

Article Analysis
・Side Effects of guanabenz
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.