[Inhibition of gastric acid secretion and motility with trospium chloride].

Author: FrühmorgenP, LuxG

Paper Details 
Original Abstract of the Article :
The present study demonstrated a significant inhibition of gastric acid secretion and gastric motility by parenteral and oral application of trospiumchloride. Oral application of a dose inhibiting gastric acid secretion was not associated with the known side effects of anticholinergic therapy like t...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/700598

データ提供:米国国立医学図書館(NLM)

Inhibition of Gastric Acid Secretion and Motility with Trospium Chloride

This study investigated the effects of trospium chloride, a medication often used to treat overactive bladder, on gastric acid secretion and motility. The researchers found that both oral and parenteral administration of trospium chloride significantly inhibited gastric acid secretion and motility. Importantly, they observed that oral administration of trospium chloride at doses that effectively inhibited gastric acid secretion did not result in the typical side effects associated with anticholinergic therapy, such as tachycardia, reduced salivary secretion, and impaired visual accommodation.

Trospium Chloride: A Potential New Avenue

The study's findings suggest that trospium chloride may have potential as a treatment for conditions related to excessive gastric acid secretion or motility. Imagine a camel traversing a scorching desert. Just as the camel can effectively regulate its body temperature and conserve water, trospium chloride may provide a similar regulatory effect on the stomach, potentially benefiting patients with gastrointestinal disorders.

A Potential Solution for Gastric Issues

The study's results offer a glimmer of hope for patients struggling with gastric issues. The possibility of a treatment with minimal side effects, like a cool oasis in a harsh desert, provides a welcome respite for those seeking relief from their symptoms. This research encourages further exploration of trospium chloride's therapeutic potential in the management of gastric disorders.

Dr.Camel's Conclusion

This study reveals that trospium chloride, like a resourceful desert traveler, can effectively manage gastric acid secretion and motility while navigating the complexities of the human digestive system. The absence of typical anticholinergic side effects, like a refreshing spring in the desert, provides a promising new avenue for therapeutic interventions.

Date :
  1. Date Completed 1978-12-29
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

700598

DOI: Digital Object Identifier

700598

Related Literature

SNS
PICO Info
in preparation
Languages

German

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