The effect of amiloride/hydrochlorothiazide combination vs furosemide plus potassium supplementation in the treatment of oedema of cardiac origin.

Author: HuikkoM, VarjorantaK, ViherkoskiM

Paper Details 
Original Abstract of the Article :
In this double-blind multicentre study efficacy and safety of amiloride/hydrochlorothiazide (A/HCTH) combination and furosemide plus potassium supplementation (FUR/P) was compared after four weeks basal period -- FUR/P period. 43 patients entered the double-blind period which lasted for ten weeks. C...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/7018361

データ提供:米国国立医学図書館(NLM)

Finding the Right Remedy for Edema of Cardiac Origin

Imagine your body is a desert, and your heart is a precious oasis. Sometimes, that oasis can get flooded, leading to edema, or fluid buildup. This study explores two different approaches to treating edema caused by heart problems. The researchers compared the effectiveness of a combination of amiloride and hydrochlorothiazide (A/HCTH) with furosemide plus potassium supplementation (FUR/P). They're like scientists studying the effects of different irrigation systems on their desert oasis, trying to find the best way to manage water levels.

Balancing the Scales of Hydration

This research explores the delicate balance of hydration, looking for the best way to manage edema caused by heart issues. They found that both A/HCTH and FUR/P were effective in controlling congestive heart failure, but A/HCTH was generally better tolerated by patients. However, they also noted the potential for hypokalaemia (low potassium levels) with A/HCTH.

Staying Hydrated in the Desert of Heart Health

For people with edema caused by heart problems, finding the right treatment is like finding a safe passage through a desert. This study reveals that both A/HCTH and FUR/P can be effective, but A/HCTH may be a better option for many patients. However, it's important to monitor potassium levels when using A/HCTH.

Dr.Camel's Conclusion

This study reminds us that even in the seemingly harsh desert of heart health, there are solutions. While finding the right treatment can be a journey, the researchers provide valuable insights into the effectiveness and safety of different approaches.

Date :
  1. Date Completed 1981-08-27
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

7018361

DOI: Digital Object Identifier

7018361

SNS
PICO Info
in preparation
Languages

English

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