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Ethambutol plus isoniazid for the treatment of pulmonary tuberculosis--a controlled trial of our regimens.

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Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Different treatment regimens for tuberculosis were compared, with a daily regimen of ethambutol and isoniazid being most effective. A weekly regimen was less effective, especially in patients who rapidly break down isoniazid.
Paper Details　
Original Abstract of the Article :
A controlled clinical trial of 4 regimens was undertaken in patients with bacteriologically positive, newly-diagnosed pulmonary tuberculosis. The regimens were: ethambutol 15 mg/kg plus isoniazid 400 mg, daily (E7H7); ethambutol 45 mg/kg plus isoniazid 15 mg/kg, twice a week (E2H2); ethambutol 90 mg...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元：
https://doi.org/10.1016/0041-3879(81)90031-3

データ提供：米国国立医学図書館（NLM）

Treating Pulmonary Tuberculosis: A Desert Oasis of Healing

The battle against tuberculosis (TB) is a long-standing struggle, requiring effective treatment regimens to eradicate this devastating disease. This research investigates the efficacy of different treatment regimens for pulmonary TB, seeking to identify the most effective and tolerable approach.

Finding the Optimal Regimen: A Desert Oasis of Success

The study compared the efficacy of four different treatment regimens for pulmonary TB, evaluating their effectiveness in achieving a favorable response and minimizing the risk of relapse. The research highlighted the importance of individualized treatment, as different regimens may be more effective for certain patient populations.

Combating TB: A Journey Through the Desert of Disease

This research provides valuable insights into the treatment of pulmonary TB, highlighting the importance of finding the most effective and tolerable regimen for each patient. The study underscores the ongoing efforts to develop new strategies for combating this challenging disease and improving patient outcomes.

Dr.Camel's Conclusion

This research offers a testament to the ongoing efforts to conquer tuberculosis. Like a skilled caravan leader navigating the vast and unforgiving desert, researchers are constantly striving to develop new and effective treatment strategies to overcome this challenging disease.

Date :
  1. Date Completed 1981-10-25
  2. Date Revised 2019-09-09
Further Info :

Pubmed ID

7022973

DOI: Digital Object Identifier

10.1016/0041-3879(81)90031-3

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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