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Mesoridazine -- a pharmacodynamic and pharmacokinetic profile.

Author: BowersP A, GershonS, SakalisG

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Mesoridazine was effective in treating schizophrenia and other psychiatric disorders. Its effectiveness in patients refractory to other neuroleptics may be related to its slow rate of inactivation.
Paper Details　
Original Abstract of the Article :
Available data on the clinical effectiveness and side effects of mesoridazine are reviewed, and an attempt is made to relate clinical efficacy to phenothiazine pharmacokinetics. Both controlled and open-label clinical studies have attested to the efficacy of mesoridazine in schizophrenia, as well as...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/7031039

データ提供：米国国立医学図書館（NLM）

Mesoridazine: A Look into its Pharmacological Profile

Mesoridazine, a phenothiazine derivative, is a drug used to treat various psychiatric disorders, including schizophrenia. The research explores the relationship between its clinical effectiveness and its pharmacokinetic properties. The study reviews available data on mesoridazine's efficacy and side effects, focusing on its slow rate of inactivation and its ability to penetrate the brain.

Mesoridazine's Mechanisms: Understanding its Actions

The researchers suggest that mesoridazine's clinical effectiveness, particularly in patients refractory to other treatments, might be related to its unique pharmacokinetic profile. Its slow inactivation allows for a sustained presence in the body, while its ability to penetrate the brain ensures that it reaches its target sites.

Mesoridazine's Implications: A Therapeutic Perspective

This research provides valuable insights into the pharmacological properties of mesoridazine. It highlights the importance of understanding the pharmacokinetic properties of drugs to optimize their clinical use. Further research is needed to fully understand the mechanisms of mesoridazine's action and its potential for treating psychiatric disorders.

Dr. Camel's Conclusion

Imagine mesoridazine as a caravan traveling through the desert. Its slow pace, like a steady camel, allows it to reach its destination, the brain, delivering its therapeutic effects. This study helps us understand the journey of mesoridazine and its impact on the mind.

Date :
  1. Date Completed 1982-02-25
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

7031039

DOI: Digital Object Identifier

7031039

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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