Timolol and metoprolol. A diurnal study of the ocular and systemic effects in glaucoma patients.

Author: EriksenJ S, NielsenN V

Paper Details 
Original Abstract of the Article :
A comparison of the diurnal effects of timolol 0.5% and metoprolol 3.0% eye drops on the intraocular pressure, blood pressure and heart rate in 10 glaucoma patients was performed in a double-masked cross-over study. Both agents produced a significant ocular hypotensive effect for more than 12 h. Tim...See full text at original site
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引用元:
https://doi.org/10.1111/j.1755-3768.1981.tb08337.x

データ提供:米国国立医学図書館(NLM)

A Head-to-Head Comparison of Timolol and Metoprolol: Ocular and Systemic Effects

This study delved into the effects of two beta-blocker eye drops, timolol and metoprolol, on intraocular pressure, blood pressure, and heart rate in glaucoma patients. The research team conducted a double-masked cross-over study, where patients received both medications in a random order, ensuring that neither the patients nor the researchers knew which medication they were receiving. The researchers aimed to compare the effectiveness of the two medications in lowering intraocular pressure and to investigate any potential systemic side effects. This study sheds light on the nuanced effects of these medications, including their duration of action, their impact on different physiological systems, and their potential for systemic effects.

Timolol and Metoprolol: A Tale of Two Beta-Blockers

This study revealed that both timolol and metoprolol effectively lowered intraocular pressure for more than 12 hours. The study found that timolol appeared to be more potent than metoprolol in terms of its effect on intraocular pressure, although both medications were effective in reducing pressure. The study also revealed that both medications could have systemic effects, with timolol lowering blood pressure and heart rate more prominently than metoprolol. These findings underscore the importance of carefully considering the individual needs of glaucoma patients and selecting the most appropriate medication based on their overall health profile.

Understanding the Systemic Effects of Ocular Medications

This study underscores the importance of considering the potential systemic effects of ocular medications, especially those that are absorbed into the bloodstream. While these medications are designed to target the eyes, they can sometimes have broader effects on other organs and systems in the body. It’s like a gentle breeze in the desert, carrying the scent of a distant oasis, but with potential to stir up dust and sand. The findings remind us that a thorough understanding of the potential side effects of medications is crucial for ensuring the safety and well-being of our patients.

Dr.Camel's Conclusion

This research compared the ocular and systemic effects of timolol and metoprolol in glaucoma patients. The findings highlight the importance of carefully considering the potential systemic effects of ocular medications and selecting the most appropriate treatment based on individual patient needs.
Date :
  1. Date Completed 1982-02-12
  2. Date Revised 2019-08-21
Further Info :

Pubmed ID

7032184

DOI: Digital Object Identifier

10.1111/j.1755-3768.1981.tb08337.x

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