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Effects of meclofenamate and captopril on blood flow to the kidney and spleen in conscious rabbits subjected to mild haemorrhage.

Author: BanksR A, BeilinL J, DavidsonL, SoltysJ

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The dependence on vasodilator prostaglandins increased in the renal and splenic vascular beds of conscious rabbits subjected to mild haemorrhage.
Paper Details　
Original Abstract of the Article :
1. Regional haemodynamic responses to mild haemorrhage were studied in three groups each of seven conscious rabbits, in the presence of either buffer, the prostaglandin cyclo-oxygenase inhibitor meclofenamate, or the kininase II inhibitor captopril. 2. Renal and splenic vasoconstriction occurred wit...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1111/j.1440-1681.1981.tb00764.x

データ提供：米国国立医学図書館（NLM）

The Intricate Dance of Blood Flow: Examining the Effects of Medications on Kidney and Spleen

Imagine the human body as a vast desert with intricate pathways and delicate balances. This study delves into the complex world of blood flow, specifically exploring the effects of medications on the kidney and spleen, two vital organs within this desert landscape.

Medications Can Influence Blood Flow in Complex Ways

This study revealed the complex interplay of medications and blood flow in the kidneys and spleen. The researchers found that meclofenamate, a prostaglandin inhibitor, and captopril, a kininase II inhibitor, both significantly impacted blood flow to these organs. This discovery highlights the importance of considering the potential effects of medications on various organs and systems, especially when dealing with conditions like haemorrhage. Like navigating a desert oasis, careful attention to the effects of medications on these delicate balances is essential.

Understanding the Impacts of Medications on Blood Flow

This study provides insights into the complex relationship between medications and blood flow in the kidneys and spleen. The findings emphasize the importance of carefully considering the potential effects of medications on blood flow to different organs, especially when dealing with conditions like haemorrhage. It's like understanding the delicate balance of water in a desert oasis: the slightest change can have a ripple effect across the entire ecosystem.

Dr.Camel's Conclusion

This study reminds us that even seemingly minor adjustments to the body's delicate balance can have significant effects on blood flow, especially in vital organs like the kidneys and spleen. It is crucial to understand the complex interactions between medications, blood flow, and the intricate workings of the body. Just as a desert oasis is a vital source of life, these organs are essential for maintaining our health and well-being.

Date :
  1. Date Completed 1982-04-12
  2. Date Revised 2019-08-25
Further Info :

Pubmed ID

7035041

DOI: Digital Object Identifier

10.1111/j.1440-1681.1981.tb00764.x

Related Literature

Article Analysis
・Effects of meclofenamate
SNS
PICO Info
in preparation
Languages

English

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