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Systematic studies with amoxapine, a new antidepressant.

Author: BanT A, FujimoriM, PetrieW M, RaghebM, WilsonW H

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Amoxapine, an antidepressant, was found to be as effective when administered in a single daily dose as when administered in divided daily doses in 35 hospitalized patients with depressive disorders. The drug was well-tolerated and had minimal effects on psychomotor performance.
Paper Details　
Original Abstract of the Article :
Amoxapine, a tricyclic dibenzoxazepine is an antidepressant which in the dosage range of 150-300 mg/day is notable for its rapid onset of action. Because of the rather long, approximately 30-hour, half-life of 8-hydroxyamoxapine, the active metabolite of amoxapine, the possibility was raised that am...See full text at original site
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引用元：
https://doi.org/10.1159/000468553

データ提供：米国国立医学図書館（NLM）

Systematic Studies with Amoxapine, a New Antidepressant

This study delves into the therapeutic potential of amoxapine, a tricyclic dibenzoxazepine with a promising rapid onset of action. The authors conducted systematic studies to investigate the effectiveness and safety of amoxapine, particularly focusing on the advantages and disadvantages of single daily dosing versus divided daily dosing.

Amoxapine: A Promising Antidepressant with Potential Advantages

The study revealed that a single daily dose of amoxapine may have certain advantages over divided daily doses, potentially improving patient compliance and reducing the perception of unwanted side effects. The findings also suggest that amoxapine's effects on psychomotor performance are clinically insignificant.

Navigating the Desert of Antidepressant Research

This study adds a valuable piece to the evolving landscape of antidepressant research. It's like discovering a hidden spring in the desert: A new drug with potential for improving the lives of those struggling with depression.

Dr.Camel's Conclusion

This study provides a comprehensive evaluation of amoxapine, highlighting its potential as a promising antidepressant. It's a reminder that even in the vast and complex desert of antidepressant research, we can discover new and effective treatments, offering hope for those seeking relief from depression.

Date :
  1. Date Completed 1982-08-26
  2. Date Revised 2019-10-31
Further Info :

Pubmed ID

7045016

DOI: Digital Object Identifier

10.1159/000468553

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Article Analysis
・Effects of amoxapine・Effects of apremilast
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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