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Buprenorphine and morphine efficacy in postoperative pain: a double-blind multiple-dose study.

Author: OuelletteR D

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Buprenorphine and morphine were found to be equally effective in relieving pain in post-surgical patients in a double-blind study involving 97 patients. Buprenorphine may be a safer alternative to morphine for acute pain due to its lower addictive potential.
Paper Details　
Original Abstract of the Article :
The analgesic activity of buprenorphine was monitored versus that of morphine in a double-blind, randomized, multiple-dose, parallel-design study involving 97 postsurgical patients. Patients could receive intramuscular injections of either buprenorphine (0.3, o.45, or 0.6 mg) or morphine (10, 15, or...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1002/j.1552-4604.1982.tb02158.x

データ提供：米国国立医学図書館（NLM）

Exploring the Efficacy of Buprenorphine and Morphine for Postoperative Pain

Managing postoperative pain is a critical aspect of patient care, akin to finding a refreshing oasis after a long journey through the desert. This study delves into the efficacy of buprenorphine, a promising alternative to morphine, in alleviating postoperative pain. The researchers conducted a double-blind study involving 97 patients, administering varying doses of either buprenorphine or morphine. Their findings reveal that buprenorphine demonstrated comparable analgesic effectiveness to morphine, offering a potentially safer and less addictive option for managing acute pain.

Buprenorphine: A Potential Oasis in the Desert of Postoperative Pain

The study's findings suggest that buprenorphine holds its own against morphine in terms of pain relief. The researchers found no statistically significant differences between the two drugs in terms of overall pain relief, pain intensity reduction, and side effects. This suggests that buprenorphine could offer a valuable alternative for patients seeking effective pain management with potentially lower addiction risks.

Easing the Pain: Navigating the Path to Recovery

This research provides a valuable roadmap for managing postoperative pain, suggesting that buprenorphine could be a more patient-centered approach. The findings encourage further exploration of buprenorphine's potential benefits in reducing the risk of opioid dependence, ultimately leading to improved patient well-being and a smoother recovery journey.

Dr. Camel's Conclusion

In the vast and often challenging landscape of pain management, buprenorphine emerges as a potential oasis, offering a comparable level of pain relief to morphine with potentially lower addiction risks. While further research is needed to fully understand its long-term effects, buprenorphine presents a promising new avenue for managing postoperative pain and improving patient outcomes.

Date :
  1. Date Completed 1982-09-10
  2. Date Revised 2019-08-25
Further Info :

Pubmed ID

7047580

DOI: Digital Object Identifier

10.1002/j.1552-4604.1982.tb02158.x

SNS
PICO Info
in preparation
Languages

English

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