Effects of concurrent drug therapy on technetium Tc-99m gluceptate biodistribution.

Author: BarkerK K, BasmadjianG P, HinkleG H, IceR D, PeekC

Paper Details 
Original Abstract of the Article :
Drug interactions with technetium Tc-99m gluceptate resulting in altered biodistribution were studied using chart review and animal tests. Charts of nine patients who had abnormal gallbladder uptake of technetium Tc-99m gluceptate during a two-year period were reviewed to obtain data such as concurr...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/7148863

データ提供:米国国立医学図書館(NLM)

The Intricate Dance of Drug Interactions: Technetium Tc-99m Gluceptate Biodistribution

The field of [nuclear medicine] often involves the use of radiopharmaceuticals, such as [technetium Tc-99m gluceptate], to diagnose and monitor various medical conditions. This study investigated the potential for [drug interactions] to alter the [biodistribution] of [technetium Tc-99m gluceptate]. Researchers examined patient charts and conducted animal studies to explore the effects of concurrent drug therapy on the radiopharmaceutical's distribution within the body.

Unveiling the Impact of Drug Interactions

The study found that [penicillamine] significantly altered the [biodistribution] of [technetium Tc-99m gluceptate], leading to increased uptake in the [gallbladder] and [small bowel]. While other drugs, such as [acetaminophen] and [trimethoprim-sulfamethoxazole], showed minimal effects, this finding highlights the importance of considering potential drug interactions when using [technetium Tc-99m gluceptate].

Navigating the Complexities of Drug Interactions

This research underscores the importance of careful attention to [drug interactions] in [nuclear medicine]. The findings emphasize the need for comprehensive patient assessments, taking into account their medication history and potential interactions with radiopharmaceuticals. The study suggests that further research is needed to fully understand the impact of various drugs on the [biodistribution] of [technetium Tc-99m gluceptate] and other radiopharmaceuticals.

Dr. Camel's Conclusion

This study is a reminder that the world of [medicine] is a delicate ecosystem, where even seemingly unrelated factors can influence one another. Just as a camel must adapt to the changing conditions of the desert, we must be mindful of potential drug interactions and ensure that our patients receive safe and effective care.

Date :
  1. Date Completed 1983-01-27
  2. Date Revised 2016-11-23
Further Info :

Pubmed ID

7148863

DOI: Digital Object Identifier

7148863

Related Literature

SNS
PICO Info
in preparation
Languages

English

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