Paper Details 
Original Abstract of the Article :
A new, microporous, uniformly reticulated preparation of cholestyramine is described. The preparation, cholpor, has a higher exchange capacity for chloride than does cholestyramine and swells very little in water. It is 15--20% more potent than chloestyramine in the in vitro binding of sodium cholat...See full text at original site
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引用元:
https://doi.org/10.1002/jps.2600671216

データ提供:米国国立医学図書館(NLM)

A New Microporous Cholestyramine Analog for Hypercholesterolemia

The world of cholesterol management is a vast desert, where we constantly search for effective ways to keep our bodies healthy. This research introduces a new, microporous, and uniformly reticulated preparation of cholestyramine, a medication used to lower cholesterol levels.

The researchers explored the potential of cholpor, a new analog of cholestyramine, to bind to bile acids in the gut, effectively lowering cholesterol levels. They compared cholpor's effectiveness to that of cholestyramine and colestipol hydrochloride.

The study found that cholpor exhibited a higher exchange capacity for chloride and a faster binding velocity than cholestyramine. It also demonstrated greater potency in binding to sodium cholate, a key bile acid involved in cholesterol metabolism. The findings suggest that cholpor could be a promising alternative to existing cholesterol-lowering medications, potentially offering improved efficacy and fewer side effects.

Cholpor: A Potential Game-Changer in Cholesterol Management

This research presents a potential breakthrough in the treatment of hypercholesterolemia. The findings suggest that cholpor could offer a more effective and tolerable alternative to existing medications, potentially improving patient outcomes.

Finding Solutions in the Desert of Cholesterol

This research is a beacon of hope in the vast desert of cardiovascular health. It suggests that innovative approaches to cholesterol management may lead to improved treatments and better outcomes for patients. Like finding a new route through a treacherous desert, this research opens up new possibilities for preventing and managing heart disease.

Dr.Camel's Conclusion

This research offers a potential oasis in the desert of cholesterol management. The development of cholpor, a new and potentially more effective cholesterol-lowering medication, could provide a much-needed solution for millions of individuals struggling with hypercholesterolemia. It's a reminder that even in the face of complex medical challenges, persistent research and innovation can lead to significant breakthroughs in the fight against disease.

Date :
  1. Date Completed 1979-02-12
  2. Date Revised 2019-07-10
Further Info :

Pubmed ID

722483

DOI: Digital Object Identifier

10.1002/jps.2600671216

Related Literature

SNS
PICO Info
in preparation
Languages

English

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